Skip to main content
Yin Wu

Dr Yin Wu

Wellcome Trust Clinical Research Career Development Fellow & Honorary Consultant Medical Oncologist

Research interests

  • Cancer

Contact details

Biography

My lab aims to understand the biology of gamma-delta T cells in human tissues and cancers. These cells are seeded perinatally and developmentally into steady-state tissues without obvious inflammatory triggers. Whilst they can readily mount local and rapid responses to cancer, their presence at steady state suggests a nuanced role which balances self-tolerance versus tumour-rejection. In juxtaposition, effective and manageable cancer immunotherapy is fundamentally a balance of tolerance versus rejection. Thus, tissue-resident gamma-delta T cells would seem critical to cancer immunosurveillance as they straddle this dichotomy, yet they remain understudied in human health and disease.

    Research

    Immunology and Immunotherapy Programme Header
    Cancer Immunology & Immunotherapy

    Cancer Immunology represents a broad field of research that studies host-tumour interactions as therapeutic targets in the treatment of cancer.

    Project status: Ongoing

    Wu Laboratory T cell thumbnail 780x450
    Wu Laboratory

    My lab aims to understand the biology of γδ T cells in human tissues and cancers.

    News

    Immune cell helps predict skin cancer patients chances of responding to treatment

    A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King’s College London, Guy’s and St...

    Gamma delta T cells: staying awake when others T cells have gone to sleep

      Research

      Immunology and Immunotherapy Programme Header
      Cancer Immunology & Immunotherapy

      Cancer Immunology represents a broad field of research that studies host-tumour interactions as therapeutic targets in the treatment of cancer.

      Project status: Ongoing

      Wu Laboratory T cell thumbnail 780x450
      Wu Laboratory

      My lab aims to understand the biology of γδ T cells in human tissues and cancers.

      News

      Immune cell helps predict skin cancer patients chances of responding to treatment

      A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King’s College London, Guy’s and St...

      Gamma delta T cells: staying awake when others T cells have gone to sleep