![Yin Wu](/newimages/folsm/person-profile/sims/yin-wu.x29fdf751.png?f=webp)
Dr Yin Wu
Wellcome Trust Clinical Research Career Development Fellow & Honorary Consultant Medical Oncologist
Research interests
- Cancer
Contact details
Biography
My lab aims to understand the biology of gamma-delta T cells in human tissues and cancers. These cells are seeded perinatally and developmentally into steady-state tissues without obvious inflammatory triggers. Whilst they can readily mount local and rapid responses to cancer, their presence at steady state suggests a nuanced role which balances self-tolerance versus tumour-rejection. In juxtaposition, effective and manageable cancer immunotherapy is fundamentally a balance of tolerance versus rejection. Thus, tissue-resident gamma-delta T cells would seem critical to cancer immunosurveillance as they straddle this dichotomy, yet they remain understudied in human health and disease.
Research
![Immunology and Immunotherapy Programme Header](/newimages/thumbnails/Immunology-seminar-series.xa626835f.jpg?w=906&h=440&crop=780,440,0,0&width=380&height=215&fit=crop&f=webp)
Cancer Immunology & Immunotherapy
Cancer Immunology represents a broad field of research that studies host-tumour interactions as therapeutic targets in the treatment of cancer.
Project status: Ongoing
![Wu Laboratory T cell thumbnail 780x450](/newimages/folsm/thumbnail-pages/sims/wu-laboratory-t-cell-thumbnail-780x450.x6b3bcd7d.png?crop=780,440,0,5&width=380&height=215&fit=crop&f=webp)
Wu Laboratory
My lab aims to understand the biology of γδ T cells in human tissues and cancers.
News
Immune cell helps predict skin cancer patients chances of responding to treatment
A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King’s College London, Guy’s and St...
![Gamma delta T cells: staying awake when others T cells have gone to sleep](/newimages/gamma-delta-t-cells.x83868b5f.png?f=webp)
Research
![Immunology and Immunotherapy Programme Header](/newimages/thumbnails/Immunology-seminar-series.xa626835f.jpg?w=906&h=440&crop=780,440,0,0&width=380&height=215&fit=crop&f=webp)
Cancer Immunology & Immunotherapy
Cancer Immunology represents a broad field of research that studies host-tumour interactions as therapeutic targets in the treatment of cancer.
Project status: Ongoing
![Wu Laboratory T cell thumbnail 780x450](/newimages/folsm/thumbnail-pages/sims/wu-laboratory-t-cell-thumbnail-780x450.x6b3bcd7d.png?crop=780,440,0,5&width=380&height=215&fit=crop&f=webp)
Wu Laboratory
My lab aims to understand the biology of γδ T cells in human tissues and cancers.
News
Immune cell helps predict skin cancer patients chances of responding to treatment
A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King’s College London, Guy’s and St...
![Gamma delta T cells: staying awake when others T cells have gone to sleep](/newimages/gamma-delta-t-cells.x83868b5f.png?f=webp)