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Timothy  Tree

Professor Timothy Tree

Professor of Immune Regulation and Immunotherapy

  • Co-Director of the Programme of Infection & Immunity

Research interests

  • Immunology

Biography

Professor Timothy Tree is a specialist in human T cell immunology with particular expertise in analysing the function of regulatory T cells in human health and disease. He currently leads a team of researchers based at Guy’s Hospital including clinicians, post-doctoral research scientists and PhD students who focus on translational medicine projects trying to unravel the basic biology of autoimmune and inflammatory disorders, such as type 1 diabetes and motor neurone disease; and develop novel therapies to halt these devastating diseases.

His work is funded by a range of medical research charities, government councils and pharmaceutical companies and includes participation in large national and international clinical trials. In addition to research activities, Tim also enjoys teaching on a wide range of undergraduate, postgraduate and professional courses including biomedical sciences and medicine. Tim was educated at Imperial College where he first read Biochemistry and then completed a doctorate in Immunology. 

    Research

    Pharmacology lab
    Tree Group

    Translational medicine projects trying to unravel the basic biology of autoimmune and inflammatory disorders and develop novel therapies to halt these devastating diseases.

    PISA Hero
    PISA: Prenatal drivers of infant ISlet Autoimmunity

    The PISA study will test the idea that different exposures in pregnancy may influence fetal development to increase the risk of childhood autoimmunity.

    Project status: Ongoing

    Transdiagnostic biological clustering
    Clinical Diagnostics Development Unit (CDDU)

    The CDDU ethos is to harmonise all methods used within the labs for the processing of clinical samples.

    News

    Psoriasis drug shows promise for treating childhood diabetes

    A drug commonly used to treat psoriasis, Ustekinumab, has been found to be effective in helping to treat children and adolescents with type 1 diabetes.

    Diabetes

    Siblings with unique genetic defect help scientists progress drug search for type 1 diabetes

    Scientist from the University of Exeter, King’s College London and Rockefeller University have collaborated to gain a new insight into type 1 diabetes

    ARTICLE DNA

    Treatment for Motor Neurone Disease shows promise

    A trial investigating a new treatment for amyotrophic lateral sclerosis (ALS) has shared promising results.

    molecules

    100 years of insulin: How immunotherapy could be the future of diabetes treatment

    This year is the 100th anniversary of the discovery of insulin.

    diabetes

    Exposure to SARS-CoV-2 during pregnancy impacts the developing immune system of the fetus

    New research from King’s suggests COVID-19 infection in the mother alters the immune system of the baby in utero.

    Pregnancy COVID-19

    Potential new treatment for ALS shows promise in clinical trial

    Researchers have disclosed the results of a potential new treatment for amyotrophic lateral sclerosis (ALS).

    als therapies promising

      Research

      Pharmacology lab
      Tree Group

      Translational medicine projects trying to unravel the basic biology of autoimmune and inflammatory disorders and develop novel therapies to halt these devastating diseases.

      PISA Hero
      PISA: Prenatal drivers of infant ISlet Autoimmunity

      The PISA study will test the idea that different exposures in pregnancy may influence fetal development to increase the risk of childhood autoimmunity.

      Project status: Ongoing

      Transdiagnostic biological clustering
      Clinical Diagnostics Development Unit (CDDU)

      The CDDU ethos is to harmonise all methods used within the labs for the processing of clinical samples.

      News

      Psoriasis drug shows promise for treating childhood diabetes

      A drug commonly used to treat psoriasis, Ustekinumab, has been found to be effective in helping to treat children and adolescents with type 1 diabetes.

      Diabetes

      Siblings with unique genetic defect help scientists progress drug search for type 1 diabetes

      Scientist from the University of Exeter, King’s College London and Rockefeller University have collaborated to gain a new insight into type 1 diabetes

      ARTICLE DNA

      Treatment for Motor Neurone Disease shows promise

      A trial investigating a new treatment for amyotrophic lateral sclerosis (ALS) has shared promising results.

      molecules

      100 years of insulin: How immunotherapy could be the future of diabetes treatment

      This year is the 100th anniversary of the discovery of insulin.

      diabetes

      Exposure to SARS-CoV-2 during pregnancy impacts the developing immune system of the fetus

      New research from King’s suggests COVID-19 infection in the mother alters the immune system of the baby in utero.

      Pregnancy COVID-19

      Potential new treatment for ALS shows promise in clinical trial

      Researchers have disclosed the results of a potential new treatment for amyotrophic lateral sclerosis (ALS).

      als therapies promising