Following his graduation from medical school and clinical training in Internal Medicine/Haematology, Dr Kordasti received his MSc in Medical Immunology and PhD in Cancer Immunology from King's College London. He established the role of regulatory T cells (Tregs) in Myelodysplastic Syndrome (MDS) and their effects on disease progression and response to treatment. In 2018, he was appointed as a senior lecturer at King's College London and continued his work, developing an interest in the immunobiology of aplastic anaemia (AA) during this period. He became a reader (Associate Professor) in Applied Cancer Immunopathology in 2022.

He is also an honorary clinical haematologist at Guy’s Hospital, and he has an interest in MDS, AA, and myeloproliferative neoplasms (MPN). His main research interest lies in the plasticity of CD4+ T cells, their interaction with the inflammatory microenvironment, and their role in the immunobiology of myeloid malignancies. Another focus of his research group is computational biology, multidimensional cytometry, and integrating multiomics data for patient stratification. Additionally, he leads an international consortium, i4MDS, focusing on standardising immune monitoring in patients with MDS.