Professor Kimberley Goldsmith PhD
Professor of Medical Statistics and Complex Intervention Methodology
Contact details
Biography
Kimberley joined KCL in 2009 and is a Biostatistician and Clinical Trials specialist with an interest in complex psychological therapy treatments. She holds an Honours degree in Biology and MSc in Microbiology and Virology from McMaster University, as well as a Master of Public Health from Oregon Health & Science University. She was awarded a National Institute for Health Research (NIHR) Doctoral Research Fellowship and graduated with a PhD in Biostatistics from King’s College London.
Kimberley has extensive experience in clinical trials in mental health and other fields, encompassing the conduct, analysis and dissemination of several single and multi-centre clinical trials. Her interest is in the study of treatment mechanisms of psychological therapies/mediation analysis, including the novel application of longitudinal structural equation models to study mediation of treatment effects. To date this work has led to a greater understanding of therapeutic mechanisms and refinement of the treatments. It is also widely applicable to the study of treatments in other disease areas and public health interventions.
Kimberley is also interested in structural equation, latent variable and longitudinal modelling more generally. Her current interest is in bringing these quantitative methods more to the fore in implementation trials, to advance the use of methods like Bayesian modelling and person-oriented mediation analysis, and to develop methods to better integrate quantitative and qualitative data in these settings.
Research Interests:
- Clinical Trials of Non-Pharmacologic Interventions
- Mediation Modelling
- Longitudinal Modelling
- Quantitative, individual and Bayesian modelling methods in Implementation Science
- Mixed methods/integration of quantitative and qualitative data in Implementation Science
Teaching:
- Clinical Trials: A Practical Approach - Module for Applied Statistical Modelling & Health Informatics PGCert
- Contemporary Psychometrics - Module for Applied Statistical Modelling & Health Informatics PGCert
- Advanced Methodology sessions for the KCL Implementation Science Masterclass
Expertise and Public Engagement:
Kimberley provides statistical expertise to a number of trial steering and data monitoring committees nationally, and as a NIHR Programme Grants for Applied Research sub-committee member. She is also a former Associate Editor of the Trials journal, and currently holds this role for the Implementation Research and Practice journal. In the past she provided expert opinion to a Guardian Science Weekly podcast on whether members of the public should be able to influence scientific publication. She is currently an EDI Theme Representative at the NIHR Maudsley BRC.
Articles and Publications
Kimberley Goldsmith - Pure Profile
Publications:
- A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc)
- Discernment of mediator and outcome measurement in the PACE trial
- Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial
- How and for whom does supportive adjustment to multiple sclerosis cognitive-behavioural therapy work? A mediated moderation analysis
- Assessing telephone-delivered cognitive–behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial
- Tutorial: The Practical Application of Longitudinal Structural EquationMediation Models in Clinical Trials
Research
Mental Health & Neuroscience Clinical Trial Statistics Group
The Mental Health & Neuroscience Clinical Trial Statistics Group leads on the design, conduct and reporting of clinical trials in mental health.
LGBTQ+ Mental Health Research Group
Research at LGBT + Mental Health investigates factors which contribute to the mental health of lesbian, gay, bisexual, transgender and other sexual and gender minority individuals (LGBT+)
Sound Young Minds
A proof of concept study of effective methodologies to evaluate musical interventions
TIES Project
Telephone delivered Incentives for Encouraging adherence to Supervised methadone consumption:development and feasibility study clinical and cost effectiveness.
Project status: Ongoing
Supporting Parents And Kids Through Lockdown Experiences (SPARKLE) Trial
A randomised control trial evaluating whether a digital public health parenting intervention can help parents to manage their children’s behaviour problems.
Project status: Ongoing
Lifecourse Epidemiology
The lifecourse epidemiology group researches developmental change, especially in childhood and adolescence. We specialise in methodology for longitudinal data including structural equation modelling.
African Youth in Mind
African Youth in Mind focuses on adapting and testing a stepped care intervention for youth with depression & anxiety in Ghana and Zimbabwe.
Project status: Ongoing
The TENDAI Study
Task shifting to treat depression and HIV medication nonadherence in low resource settings
Project status: Ongoing
Causal Analysis & Evaluation
The Causal Modelling Group comprises statisticians and methodologists at King’s College London interested in drawing causal inferences from study data.
News
Providing mental health support in peace efforts helps alleviate PTSD and depression
New study shows group counselling and one -on-one peacebuilding activities improve mental health in Nigeria
A new generation of Inspiring Women at the IoPPN
28 new portraits of internationally recognised female professors at the Faculty have been added to IoPPN’s ‘Inspiring Women’ exhibition, celebrating the...
Evaluating effectiveness of treatment for adults with chronic fatigue syndrome
A new systematic review of 15 studies, led by researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) and South London and Maudsley...
Professor Melanie Abas receives £2.75m in UKRI funding
Professor Melanie Abas, with members of a new Global Health Research Group, has received £2.75m in NIHR funding to learn how best to treat depression and...
New guidelines to improve reporting standards of studies that aim to understand causal mechanisms
Researchers have developed a new set of guidelines for reporting mediation analyses in health research.
Research
Mental Health & Neuroscience Clinical Trial Statistics Group
The Mental Health & Neuroscience Clinical Trial Statistics Group leads on the design, conduct and reporting of clinical trials in mental health.
LGBTQ+ Mental Health Research Group
Research at LGBT + Mental Health investigates factors which contribute to the mental health of lesbian, gay, bisexual, transgender and other sexual and gender minority individuals (LGBT+)
Sound Young Minds
A proof of concept study of effective methodologies to evaluate musical interventions
TIES Project
Telephone delivered Incentives for Encouraging adherence to Supervised methadone consumption:development and feasibility study clinical and cost effectiveness.
Project status: Ongoing
Supporting Parents And Kids Through Lockdown Experiences (SPARKLE) Trial
A randomised control trial evaluating whether a digital public health parenting intervention can help parents to manage their children’s behaviour problems.
Project status: Ongoing
Lifecourse Epidemiology
The lifecourse epidemiology group researches developmental change, especially in childhood and adolescence. We specialise in methodology for longitudinal data including structural equation modelling.
African Youth in Mind
African Youth in Mind focuses on adapting and testing a stepped care intervention for youth with depression & anxiety in Ghana and Zimbabwe.
Project status: Ongoing
The TENDAI Study
Task shifting to treat depression and HIV medication nonadherence in low resource settings
Project status: Ongoing
Causal Analysis & Evaluation
The Causal Modelling Group comprises statisticians and methodologists at King’s College London interested in drawing causal inferences from study data.
News
Providing mental health support in peace efforts helps alleviate PTSD and depression
New study shows group counselling and one -on-one peacebuilding activities improve mental health in Nigeria
A new generation of Inspiring Women at the IoPPN
28 new portraits of internationally recognised female professors at the Faculty have been added to IoPPN’s ‘Inspiring Women’ exhibition, celebrating the...
Evaluating effectiveness of treatment for adults with chronic fatigue syndrome
A new systematic review of 15 studies, led by researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) and South London and Maudsley...
Professor Melanie Abas receives £2.75m in UKRI funding
Professor Melanie Abas, with members of a new Global Health Research Group, has received £2.75m in NIHR funding to learn how best to treat depression and...
New guidelines to improve reporting standards of studies that aim to understand causal mechanisms
Researchers have developed a new set of guidelines for reporting mediation analyses in health research.