The Mental Health & Neuroscience Clinical Trial Statistics Group is led by Professor Ben Carter and situated at the Denmark Hill Campus within the Institute of Psychology, Psychiatry & Neuroscience (IoPPN).
Our mission revolves around the meticulous methodological oversight of clinical trials in mental health and neuroscience. We have an unwavering commitment to the development of trial designs which possess the resilience to provide answers to pivotal clinical inquiries. We operate in close collaboration with clinical colleagues spanning King's Health Partners (KHP) and the broader UK clinical academic community.
We are dedicated to increasing capacity in clinical trial statisticians at the IoPPN while assuring robust clinical trial quality – a commitment firmly rooted in the principles of Good Clinical Practice (GCP).
The team is part of the King's Clinical Trials Unit (KCTU) collaboration. We adhere to relevant Standard Operating Procedures managed by the KCTU Quality Assurance team.
We are organised into the following themes:
- Hepatology and Addiction Science (Ben Carter, Francesca Maher, Kimberley Goldsmith, Hassan Jafari)
- Affective Disorders (Ben Carter, Kirsty James, Dominic Stringer, Kimberley Goldsmith, Megan McGovern, Meredith Martyn, Nick Beckley-Hoelscher, Danielle Edwards)
- Eating Disorders (Ben Carter, Kirsty James, Dominic Stringer, Kimberley Goldsmith, Sabine Landau, Meredith Martyn)
- Child and Adolescent Mental Health (Ben Carter, Richard Emsley, Kimberley Goldsmith, Kirsty James, Dominic Stringer, Harper Clees-Baron, Sabine Landau, Oliver Pearson, Nick Beckley-Hoelscher, Danielle Edwards)
- Global Mental Health (Kimberly Goldsmith, Megan McGovern, Richard Emsley, Sam Cross)
- Persistent Physical Symptoms (Kimberley Goldsmith, Kirsty James, Sabine Landau)
- Psychosis (Richard Emsley, Callum Glen, Hassan Jafari, Dominic Stringer, Anca Chis Ster)
- Neurodevelopmental Disorders (Ben Carter, Richard Emsley, Sabine Landau, Meredith Martyn)
- Neuroscience (Francesa Maher, Ben Carter, Kirsty James, Dominic Stringer, Petrina Chu, Nick Beckley-Hoelscher)
- Public Health (Ben Carter, Meredith Martyn, Petrina Chu, Francesca Maher, Anca Chis Ster)
People
Lecturer
Research Fellow (Statistician)
Senior Lecturer in Biostatistics, Biostatistics & Health Informatics
Professor of Medical Statistics
Research Fellow
Research Fellow (Principal Statistician)
Publications
- Multicentre, England-wide randomised controlled trial of the ‘Foundations’ smartphone application in improving mental health and well-being in a healthcare worker population | The British Journal of Psychiatry | Cambridge Core
- Clinical effectiveness and cost-effectiveness of a brief accessible cognitive behavioural therapy programme for stress in school-aged adolescents (BESST): a cluster randomised controlled trial in the UK - The Lancet Psychiatry
- Exposure-based cognitive-behaviour therapy for anxiety-related disorders in pregnancy (ADEPT): Results of a feasibility randomised controlled trial of time-intensive versus weekly CBT - ScienceDirect
- Long-term psychosocial outcomes of low-dose CT screening: results of the UK Lung Cancer Screening randomised controlled trial | Thorax (bmj.com)
- Randomized Crossover Trial of Conventional vs Virtual Chromoendoscopy for Colitis Surveillance: Dysplasia Detection, Feasibility, and Patient Acceptability (CONVINCE) | Inflammatory Bowel Diseases | Oxford Academic (oup.com)
- Management of fraudulent participants in online research: Practical recommendations from a randomized controlled feasibility trial - International Journal of Eating Disorders
- The Effectiveness and Cost-Effectiveness of a Universal Digital Parenting Intervention Designed and Implemented During the COVID-19 Pandemic: Evidence From a Rapid-Implementation Randomized Controlled Trial Within a Cohort - Journal of Medical Internet Research
- A systematic literature review of randomized controlled trials evaluating prognosis following treatment for adults with chronic fatigue syndrome - Psychological Medicine
- A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc) - Nature Communications
- Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial - BMJ Open
- Assessing telephone-delivered cognitive–behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial - Gut
- Effect of Vitamin D Supplementation on Outcomes in People With Early Psychosis: The DFEND Randomized Clinical Trial – JAMA Network Open
- Cognitive Remediation Works But How Should We Provide It? An Adaptive Randomized Controlled Trial of Delivery Methods Using a Patient Nominated Recovery Outcome in First-Episode Participants – Schizophrenia Bulletin
- A Novel Group Parenting Intervention for Emotional and Behavioral Difficulties in Young Autistic Children: Autism Spectrum Treatment and Resilience (ASTAR): A Randomized Controlled Trial – Journal of the American Academy of Child & Adolescent Psychiatry
- Comparison of a theoretically driven cognitive therapy (the Feeling Safe Programme) with befriending for the treatment of persistent persecutory delusions: a parallel, single-blind, randomised controlled trial - PubMed (nih.gov)
News
Multi-site trial uses digital avatars to effectively reduce distressing voices in psychosis
A novel therapy using computer-generated avatars has found to be an effective way of helping people with psychosis reduce the distress and frequency with...
Day workshop in Cognitive Behavioural Therapy effectively reduces depression in 16-18 year olds
The Brief Educational workshops in Secondary Schools Trial found a day-long CBT course is an effective means of improving young people's mental health.
£3.2m funding to test the ADVANCE-D Programme for men with substance use problems serving community sentences for partner abuse
The National Institute for Health Research (NIHR) has awarded £3.2 million funding to principal investigator, Professor Gail Gilchrist (King’s College London)...
People
Lecturer
Research Fellow (Statistician)
Senior Lecturer in Biostatistics, Biostatistics & Health Informatics
Professor of Medical Statistics
Research Fellow
Research Fellow (Principal Statistician)
Publications
- Multicentre, England-wide randomised controlled trial of the ‘Foundations’ smartphone application in improving mental health and well-being in a healthcare worker population | The British Journal of Psychiatry | Cambridge Core
- Clinical effectiveness and cost-effectiveness of a brief accessible cognitive behavioural therapy programme for stress in school-aged adolescents (BESST): a cluster randomised controlled trial in the UK - The Lancet Psychiatry
- Exposure-based cognitive-behaviour therapy for anxiety-related disorders in pregnancy (ADEPT): Results of a feasibility randomised controlled trial of time-intensive versus weekly CBT - ScienceDirect
- Long-term psychosocial outcomes of low-dose CT screening: results of the UK Lung Cancer Screening randomised controlled trial | Thorax (bmj.com)
- Randomized Crossover Trial of Conventional vs Virtual Chromoendoscopy for Colitis Surveillance: Dysplasia Detection, Feasibility, and Patient Acceptability (CONVINCE) | Inflammatory Bowel Diseases | Oxford Academic (oup.com)
- Management of fraudulent participants in online research: Practical recommendations from a randomized controlled feasibility trial - International Journal of Eating Disorders
- The Effectiveness and Cost-Effectiveness of a Universal Digital Parenting Intervention Designed and Implemented During the COVID-19 Pandemic: Evidence From a Rapid-Implementation Randomized Controlled Trial Within a Cohort - Journal of Medical Internet Research
- A systematic literature review of randomized controlled trials evaluating prognosis following treatment for adults with chronic fatigue syndrome - Psychological Medicine
- A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc) - Nature Communications
- Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial - BMJ Open
- Assessing telephone-delivered cognitive–behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial - Gut
- Effect of Vitamin D Supplementation on Outcomes in People With Early Psychosis: The DFEND Randomized Clinical Trial – JAMA Network Open
- Cognitive Remediation Works But How Should We Provide It? An Adaptive Randomized Controlled Trial of Delivery Methods Using a Patient Nominated Recovery Outcome in First-Episode Participants – Schizophrenia Bulletin
- A Novel Group Parenting Intervention for Emotional and Behavioral Difficulties in Young Autistic Children: Autism Spectrum Treatment and Resilience (ASTAR): A Randomized Controlled Trial – Journal of the American Academy of Child & Adolescent Psychiatry
- Comparison of a theoretically driven cognitive therapy (the Feeling Safe Programme) with befriending for the treatment of persistent persecutory delusions: a parallel, single-blind, randomised controlled trial - PubMed (nih.gov)
News
Multi-site trial uses digital avatars to effectively reduce distressing voices in psychosis
A novel therapy using computer-generated avatars has found to be an effective way of helping people with psychosis reduce the distress and frequency with...
Day workshop in Cognitive Behavioural Therapy effectively reduces depression in 16-18 year olds
The Brief Educational workshops in Secondary Schools Trial found a day-long CBT course is an effective means of improving young people's mental health.
£3.2m funding to test the ADVANCE-D Programme for men with substance use problems serving community sentences for partner abuse
The National Institute for Health Research (NIHR) has awarded £3.2 million funding to principal investigator, Professor Gail Gilchrist (King’s College London)...
Group lead
Professor of Medical Statistics