Professor Frances Williams Academics Supervisors Professor of Genomic Epidemiology Contact details frances.williams@kcl.ac.uk
Paraspinal muscle quality in chronic low back pain: a systematic review and meta-analysis of muscle atrophy and fat infiltration Common inflammatory proteins linking frailty and area-level deprivation as key drivers of cardiovascular risk in women A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease Multifluid Metabolomics Identifies Novel Biomarkers for Irritable Bowel Syndrome Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One-Sample Mendelian Randomization Study Treatment response in rheumatoid arthritis is predicted by the microbiome: a large observational study in UK DMARD-naive patients Decomposing the genetic background of chronic back pain A multi-trait approach identified 7 novel genes for back pain Chronic widespread musculoskeletal pain shares a highly heritable latent pathway with atherosclerosis and arterial stiffness A Mendelian randomization study finds no evidence for causal effects of C-reactive protein (CRP) on chronic pain conditions Quantitative sensory testing and chronic pain syndromes: a cross-sectional study from TwinsUK The association of lumbar intervertebral disc degeneration with low back pain is modified by underlying genetic propensity to pain Glycoprotein Acetyls Is a Novel Biomarker Predicting Cardiovascular Complications in Rheumatoid Arthritis Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus No evidence of association between either Modic change or disc degeneration and five circulating inflammatory proteins Evidence of causal effects of blood pressure on back pain and back pain on type II diabetes provided by a bidirectional Mendelian randomization study Insights into the pleiotropic relationships between chronic back pain and inflammation-related musculoskeletal conditions: rheumatoid arthritis and osteoporotic abnormalities Repurposing Antihypertensive and Statin Medications for Spinal Pain: A Mendelian Randomization Study Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain Bidirectional Mendelian Randomization Study of Personality Traits Reveals a Positive Feedback Loop Between Neuroticism and Back Pain Multi-Trait Exome-Wide Association Study of Back Pain-Related Phenotypes Noncoding rare variants in PANX3 are associated with chronic back pain Does Dysbiosis Play a Role in Age-Related Hearing Impairment? Genotype-by-environment interactions in chronic back pain GlycA and CRP Are Genetically Correlated: Insight into the Genetic Architecture of Inflammageing Intensive therapy for moderate established rheumatoid arthritis: the TITRATE research programme Accurate phenotypic classification and exome sequencing allow identification of novel genes and variants associated with adult-onset hearing loss Long-COVID fatigue is not predicted by pre-pandemic plasma IL-6 levels in mild COVID-19 Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss Genetic and environmental correlational structure among metabolic syndrome endophenotypes Understanding the complex genetic architecture connecting rheumatoid arthritis, osteoporosis, and inflammation: discovering causal pathways Author Correction: Attributes and predictors of long COVID (Nature Medicine, (2021), 27, 4, (626-631), 10.1038/s41591-021-01292-y) Shared genetic architecture between rheumatoid arthritis and varying osteoporotic phenotypes Evidence for infection in intervertebral disc degeneration: a systematic review Baseline predictors of remission, pain and fatigue in rheumatoid arthritis: the TITRATE trial Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci Genome-wide association studies of low back pain and lumbar spinal disorders using electronic health record data identify a locus associated with lumbar spinal stenosis Genome-wide association study suggests that variation at the RCOR1 locus is associated with tinnitus in UK Biobank Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable New genetic markers of age-related hearing loss Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease Intelligence-Based Spine Care Model: A New Era of Research and Clinical Decision-Making An association between chronic widespread pain and the gut microbiome Sex- and age-specific genetic analysis of chronic back pain The clinical effectiveness of intensive management in moderate established rheumatoid arthritis: The titrate trial Covid-19 and chronic fatigue View all publications
29 June 2022 Deputy Director of King's Clinical Academic Training Office (KCATO) appointed Professor Catherine Evans will join as the second Deputy Director of the KCATO.