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Thalia Eley

Professor Thalia Eley PhD

Professor of Developmental Behavioural Genetics

  • Deputy Head of Department, Social, Genetic & Developmental Psychiatry Centre

Research interests

  • Mental Health

Biography

Thalia Eley is Professor of Developmental Behavioural Genetics at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London. She leads the Emotional Development, Intervention and Treatment (EDIT) lab, and her work focuses on the interplay between genetic and environmental factors in the development and treatment of anxiety and depression.

For her undergraduate degree, she studied Social and Political Sciences, with a focus on psychology, at Trinity College Cambridge. She undertook her PhD at the Institute of Child Health, University College London, where she studied the role of genetic and environmental influences on depression and anxiety in young people. After two MRC research fellowships, she became a member of academic staff at the Institute of Psychiatry, Psychology & Neuroscience and was promoted to Professor in 2013.

Her work is highly interdisciplinary using both the twin design and molecular genetic approaches, and drawing on cognitive, clinical and developmental psychology. She has written over 140 empirical papers and received numerous awards including the Spearman Medal from the British Psychological Society, the Lilly-Molecular Psychiatry Award, and most recently the James Shields Lifetime Achievement Award from the International Society for Twin Studies. She is one of the Chairs of the Psychiatric Genomics Consortium Anxiety Group.

Professor Eley is passionate about enabling early career researchers and was Chair of the Research and Innovation Committee for over five years, developing and leading numerous initiatives aimed at supporting this group. She is keen to see greater diversity in those conducting, and taking part, in scientific research.

Research interests

Professor Eley is particularly interested in finding ways in which genetic approaches can inform psychological practice as well as theory. Using molecular genetics, she is exploring the role of specific genetic markers in the development of anxiety and depression, and as predictors of psychological therapies response for these conditions. With her close colleague Professor Gerome Breen, head of the NIHR Maudsley BioResource Centre, she is leading new Genetics Links to Anxiety and Depression (GLAD) Study. Watch a video of them describing the purpose of this study here, and an animation about the study here. She is particularly excited about this area of work as it has the potential to be useful in making clinical decisions.

She is also keen to understand why anxiety and depression tend to run in families, and whether this is due to sharing home life or whether it is due to sharing genes. She is the Director of the Twins Early Development Study (TEDS), the largest longitudinal twin birth cohort in the UK. As the twins reach their mid-twenties, the team is particularly excited about recruiting the next generation into the Children of TEDS (CoTEDS) Study.

Expertise and public engagement

The EDIT lab runs a blog. The GLAD Study participants are recruited via the media and social media, so the team has written numerous articles (and had lots of articles written about them), as well as featuring on TV and traditional media.

Her team has worked closely with many charities (e.g. MIND) and with the British Psychological Society and Royal College of Psychiatrists all of whom supported and promoted the GLAD study.

Professor Eley has written blogs for Mental Elf and have spoken at Pint of Science twice.

She has given many lecturers about her work:

  • Inaugural lecture (Autumn 2013) here, in which she gave an overview of the work she undertook from her PhD in the 1990s until 2013 when she became a professor.
  • Therapy genetics lecture (Spring 2017) here, as part of the Stockholm Psychiatry lecture series.
  • This lecture is a brief update of the work of the Psychiatric Genetics Consortium Anxiety group (Spring 2020).

Awards

  • 2021 Fellow of the Academy of Medical Sciences
  • 2019 KCL University Research Project of the year (GLAD Study)
  • 2017 James Shields Lifetime Achievement Award from the International Society for Twin Studies
  • 2017 KCL Graduate School IoPPN Supervisory Excellence Award
  • 2004 Lilly-Molecular Psychiatry Award
  • 2002 British Psychological Society Spearman Medal

Teaching:

  • SGDP Education lead
  • Assessment Sub-Board Chair for SGDP DEV-PP Masters programme
  • Teaching on genetics of anxiety, depression and treatment response.
  • Grant writing training.

    Research

    TEDS logo - 780 x 440px
    TEDS: Twins Early Development Study

    The Twin Early Development Study (TEDS) is one of the leading large-scale twin studies in the world. Starting in 1994, it has followed twins born in England and Wales throughout their childhood and adolescence and has now continued into early adulthood.

    EDIT Lab logo 3 v.2
    The Emotional Development, Interventions and Treatment (EDIT) Lab

    The EDIT lab is led by Prof Thalia Eley and consists of post doctoral researchers, PhD students, and both undergraduate and masters students. We study genetic and environmental influences on the development and treatment of anxiety and depression. We are based at the SGDP Centre at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London.

    GLAD: Genetic Links to Anxiety and Depression

    The GLAD Study is the largest anxiety and depression project ever undertaken. It was launched in September 2018.

    Project status: Ongoing

    CoTEDS Thumbnail 17-10-17
    Children of TEDS (CoTEDS) Study

    The aim of this project is to explore the origins of the development of emotional disorders.

    Project status: Ongoing

    FLARe: Fear Learning and Anxiety Response

    FLARe aims to model the processes underlying the development, maintenance and treatment of anxiety disorders, and post-treatment relapse.

    Project status: Ongoing

    G1219: Genesis 1219

    G1219 is a longitudinal study that aims to examine the interplay between genes and the environment on the development of anxiety and depression over time.

    Project status: Completed

    RAMP study logo promo
    Repeated Assessment of Mental health in Pandemics (RAMP)

    The Repeated Assessment of Mental health in Pandemics (RAMP) study is a research project assessing the effect of COVID-19 on the mental health and wellbeing of the population.

    News

    £4.8 million Wellcome funding to predict outcomes following anxiety treatment

    Wellcome has awarded over £4.8m for researchers to predict individual outcomes following psychological treatments for anxiety, and to identify genetic and...

    therapy two people

    UK Longitudinal Linkage Collaboration awarded £6.4m

    New funding from MRC/ESRC will allow partnership between leading UK longitudinal studies, including King’s-led studies GLAD and EDGI UK will enable...

    UK LLC logo

    Professor Thalia Eley elected as Fellow of the Academy of Medical Sciences

    Professor Eley is one of 50 new Fellows to be elected to the prestigious Academy of Medical Sciences

    Professor Thalia Eley

    Twins Early Development Study receives £3.2million funding from MRC

    Successful grant renewal from Medical Research Council (MRC) will fund pioneering Twin Early Development Study until 2025.

    TEDS logo - 780 x 440px

    Features

    Exploring research into anxiety disorders this Mental Health Awareness Week

    This year, Mental Health Awareness Week took place Monday 15 - Sunday 21 June, following the theme ‘anxiety’. Anxiety is a normal emotion in us all, but...

    Website Hero (1)

      Research

      TEDS logo - 780 x 440px
      TEDS: Twins Early Development Study

      The Twin Early Development Study (TEDS) is one of the leading large-scale twin studies in the world. Starting in 1994, it has followed twins born in England and Wales throughout their childhood and adolescence and has now continued into early adulthood.

      EDIT Lab logo 3 v.2
      The Emotional Development, Interventions and Treatment (EDIT) Lab

      The EDIT lab is led by Prof Thalia Eley and consists of post doctoral researchers, PhD students, and both undergraduate and masters students. We study genetic and environmental influences on the development and treatment of anxiety and depression. We are based at the SGDP Centre at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London.

      GLAD: Genetic Links to Anxiety and Depression

      The GLAD Study is the largest anxiety and depression project ever undertaken. It was launched in September 2018.

      Project status: Ongoing

      CoTEDS Thumbnail 17-10-17
      Children of TEDS (CoTEDS) Study

      The aim of this project is to explore the origins of the development of emotional disorders.

      Project status: Ongoing

      FLARe: Fear Learning and Anxiety Response

      FLARe aims to model the processes underlying the development, maintenance and treatment of anxiety disorders, and post-treatment relapse.

      Project status: Ongoing

      G1219: Genesis 1219

      G1219 is a longitudinal study that aims to examine the interplay between genes and the environment on the development of anxiety and depression over time.

      Project status: Completed

      RAMP study logo promo
      Repeated Assessment of Mental health in Pandemics (RAMP)

      The Repeated Assessment of Mental health in Pandemics (RAMP) study is a research project assessing the effect of COVID-19 on the mental health and wellbeing of the population.

      News

      £4.8 million Wellcome funding to predict outcomes following anxiety treatment

      Wellcome has awarded over £4.8m for researchers to predict individual outcomes following psychological treatments for anxiety, and to identify genetic and...

      therapy two people

      UK Longitudinal Linkage Collaboration awarded £6.4m

      New funding from MRC/ESRC will allow partnership between leading UK longitudinal studies, including King’s-led studies GLAD and EDGI UK will enable...

      UK LLC logo

      Professor Thalia Eley elected as Fellow of the Academy of Medical Sciences

      Professor Eley is one of 50 new Fellows to be elected to the prestigious Academy of Medical Sciences

      Professor Thalia Eley

      Twins Early Development Study receives £3.2million funding from MRC

      Successful grant renewal from Medical Research Council (MRC) will fund pioneering Twin Early Development Study until 2025.

      TEDS logo - 780 x 440px

      Features

      Exploring research into anxiety disorders this Mental Health Awareness Week

      This year, Mental Health Awareness Week took place Monday 15 - Sunday 21 June, following the theme ‘anxiety’. Anxiety is a normal emotion in us all, but...

      Website Hero (1)