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Tanya  Shaw

Dr Tanya Shaw

Interim Head of Department, Inflammation Biology

  • Head of Anatomy

Research interests

  • Immunology

Biography

Tanya specialises in wound repair and scarring, with a focus on cell differentiation and extracellular matrix. She gained her PhD in Cellular and Molecular Medicine at the University of Ottawa (Canada), researching ovarian cancer under the supervision of Professor Barbara Vanderhyden. Tanya then moved to the UK, where she began working on wound repair as a postdoctoral fellow in the lab of Professor Paul Martin at the University of Bristol. She established her independent research group at St George’s, University of London, where she worked from 2009-2014. In 2014 she joined King’s, where she is now a team leader in the Centre for Inflammation Biology and Cancer Immunology, in the School of Immunology & Microbial Sciences, and is a member of the Anatomy teaching department.

Research Interests

  • normal and pathological scar formation (namely skin scars, but also other fibrotic conditions, including fibrotic tumour stroma)
  • the architecture of fibrotic extracellular matrix
  • cell differentiation events in skin wound healing
  • cross-talk between the extracellular matrix and immune cells
  • common molecular mediators of fibrosis and pain
  • dermis development

    Research

    test-tubes-hero-banner1903x558
    Shaw Lab

    The Shaw Lab aims to understand the cell and molecular mechanisms underlying scarring.

    From Dev Biology to Regen Medicine-hero
    From Developmental Biology to Regenerative Medicine

    Understanding organ development and tissue regeneration provides a framework for elucidating disease mechanisms as well as for developing new therapeutics.

    Spatial Biology hero
    Spatial Biology Network

    The Spatial Biology Network is a cross-faculty research interest group that brings together researchers from various disciplines, ranging from technology development and molecular biology, to bioinformatics and clinical translational research, to explore the complexity of spatial biology.

    Cells
    King’s MechanoBiology Centre (KMBC)

    The King’s MechanoBiology Centre gives a common platform for researchers across different disciplines with complementary interests in mechanobiology

    MBRH-LOGO
    The Multiscale Biofilm Research Hub (MBRH)

    The Multiscale Biofilm Research Hub (MBRH) has been established to promote interdisciplinary interactions and focus microbial biofilm related research at King’s.

    MBRH theme2
    Dermatological and non-mucosal biofilms

    We are studying the role of biofilms in dermatitis, chronic pain, diabetic ulcers, nail infections and chronic wounds.

    Project status: Ongoing

    News

    King's researchers highlight new potential therapies for scarring

    New insights from studying keloid scars could provide novel treatments for fibrosis

    Tanya Shaw keloid scar publication v2

    Excessive scarring shown to be associated with atopic eczema, hypertension and musculoskeletal diseases

    Researchers find that excessive keloid and hypertrophic scarring co-occurs with specific conditions, while ethnicity also plays a part.

    Keloid Scar

    Tanya teaches in the Anatomy Department, hosting lab and library project students, and acting as Deputy Module Organiser for the 2nd year BSc course 5BBA2021 Structural Basis of Human Function. She also provides significant anatomy teaching for dentistry students at King's and contributes to the Immunology MSc program through lectures and lab projects.

      Research

      test-tubes-hero-banner1903x558
      Shaw Lab

      The Shaw Lab aims to understand the cell and molecular mechanisms underlying scarring.

      From Dev Biology to Regen Medicine-hero
      From Developmental Biology to Regenerative Medicine

      Understanding organ development and tissue regeneration provides a framework for elucidating disease mechanisms as well as for developing new therapeutics.

      Spatial Biology hero
      Spatial Biology Network

      The Spatial Biology Network is a cross-faculty research interest group that brings together researchers from various disciplines, ranging from technology development and molecular biology, to bioinformatics and clinical translational research, to explore the complexity of spatial biology.

      Cells
      King’s MechanoBiology Centre (KMBC)

      The King’s MechanoBiology Centre gives a common platform for researchers across different disciplines with complementary interests in mechanobiology

      MBRH-LOGO
      The Multiscale Biofilm Research Hub (MBRH)

      The Multiscale Biofilm Research Hub (MBRH) has been established to promote interdisciplinary interactions and focus microbial biofilm related research at King’s.

      MBRH theme2
      Dermatological and non-mucosal biofilms

      We are studying the role of biofilms in dermatitis, chronic pain, diabetic ulcers, nail infections and chronic wounds.

      Project status: Ongoing

      News

      King's researchers highlight new potential therapies for scarring

      New insights from studying keloid scars could provide novel treatments for fibrosis

      Tanya Shaw keloid scar publication v2

      Excessive scarring shown to be associated with atopic eczema, hypertension and musculoskeletal diseases

      Researchers find that excessive keloid and hypertrophic scarring co-occurs with specific conditions, while ethnicity also plays a part.

      Keloid Scar

      Tanya teaches in the Anatomy Department, hosting lab and library project students, and acting as Deputy Module Organiser for the 2nd year BSc course 5BBA2021 Structural Basis of Human Function. She also provides significant anatomy teaching for dentistry students at King's and contributes to the Immunology MSc program through lectures and lab projects.