Professor Gráinne McAlonan Supervisors Professor of Translational Neuroscience Director, NIHR Maudsley Biomedical Research Centre. Head of Department, Forensic and Neurodevelopmental Sciences. Research subject areas Mental Health Neuroscience Contact details grainne.mcalonan@kcl.ac.uk
NIHR Maudsley Biomedical Research Centre Brain Imaging in Babies (BIBS) EU-AIMS (European Autism Interventions)
Transcriptomic decoding of surface-based imaging phenotypes and its application to pharmacotranscriptomics Quantifying Fetal Periventricular White Matter Development Using Multimodal MRI Locus coeruleus tonic upregulation increases selectivity to inconspicuous auditory information in autistic compared to non-autistic individuals: a combined pupillometry and electroencephalography study Transcriptomic decoding of surface-based imaging phenotypes and its application to pharmacotranscriptomics General and autism-related neurodevelopmental difficulties in Biliary Atresia. Patterns of Brain Maturation in Autism and Their Molecular Associations Frontal and occipital brain glutathione levels are unchanged in autistic adults European Autism GEnomics Registry (EAGER): Protocol for a multicentre cohort study and registry The ‘PSILAUT’ protocol: an experimental medicine study of autistic differences in the function of brain serotonin targets of psilocybin Retinal GABAergic Alterations in Adults with Autism Spectrum Disorder Clinical, socio-demographic, and parental correlates of early autism traits in a community cohort of toddlers Editorial Perspective: Bridging the translational neuroscience gap in autism – development of the ‘shiftability’ paradigm Comparison of an online adaptation of the Autism Diagnostic Observation Schedule-2 with its in-person version in an adult autism diagnostic service Genetic relationship between the immune system and autism Immunogenetics of autism spectrum disorder: A systematic literature review Exploratory evidence for differences in GABAergic regulation of auditory processing in autism spectrum disorder Bridge-building between communities: Imagining the future of biomedical autism research Development of neonatal brain functional centrality and alterations associated with preterm birth Bridging the translational neuroscience gap: Development of the ‘shiftability’ paradigm and an exemplar protocol to capture psilocybin-elicited ‘shift’ in neurobiological mechanisms in autism Neonatal brain dynamic functional connectivity in term and preterm infants and its association with early childhood neurodevelopment From mechanisms to markers: novel noninvasive EEG proxy markers of the neural excitation and inhibition system in humans Development of neonatal brain functional centrality and alterations associated with preterm birth From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells Cell line specific alterations in genes associated with dopamine metabolism and signaling in midbrain dopaminergic neurons derived from 22q11.2 deletion carriers with elevated dopamine synthesis capacity The developing brain structural and functional connectome fingerprint Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter: A randomised placebo-controlled single-dose crossover trial Author Correction: Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans (Nature Communications, (2020), 11, 1, (1160), 10.1038/s41467-020-14845-5) Neonatal multi-modal cortical profiles predict 18-month developmental outcomes Adults with autism spectrum disorder and the criminal justice system: An investigation of prevalence of contact with the criminal justice system, risk factors and sex differences in a specialist assessment service GABAB receptor modulation of visual sensory processing in adults with and without autism spectrum disorder Mapping brain structural differences and neuroreceptor correlates in Parkinson’s disease visual hallucinations Effects of gestational age at birth on perinatal structural brain development in healthy term-born babies Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons Preterm birth alters the development of cortical microstructure and morphology at term-equivalent age Small P values may not yield robust findings: an example using REST-meta-PD Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin Maternal depression during pregnancy alters infant subcortical and midbrain volumes. T1-Weighted/T2-Weighted Ratio Mapping at 5 Months Captures Individual Differences in Behavioral Development and Differentiates Infants at Familial Risk for Autism from Controls The developing brain structural and functional connectome fingerprint Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine Neurometabolite Mapping Highlights Elevated Myo-inositol Profiles within the Developing Brain in Down Syndrome Phenotyping the Preterm Brain: Characterizing Individual Deviations from Normative Volumetric Development in Two Large Infant Cohorts Atypical Neurogenesis in Induced Pluripotent Stem Cells From Autistic Individuals Interferon-γ signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers: A randomized double-blind 7-Tesla pharmacological MRS study Multidisciplinary: research priorities for the COVID-19 pandemic Early maturation of the social brain: How brain development provides a platform for the acquisition of social-cognitive competence Atypical neurogenesis in induced pluripotent stem cell (iPSC) from autistic individuals Development of Microstructural and Morphological Cortical Profiles in the Neonatal Brain View all publications
20 June 2025 Experts with lived experience address mental health stigma The community engagement event, “Voices of Experience: Breaking Mental Health Stigma”, was hosted at…