Professor Phil Blower Academics Supervisors Professor of Imaging Chemistry and Head of Department of Imaging Chemistry and Biology Research subject areas Chemistry Contact details philip.blower@kcl.ac.uk
Ion beam imaging shows selective thallium-201 uptake in cell nuclei: impact on cellular dosimetry and radiotoxicity of Auger electron-emitters Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting Subcellular Mapping of Thallium (Tl) Delivered by Prussian Blue Nanoparticles in Lung Cancer Cells In vitro and in vivo radiotoxicity and biodistribution of thallium-201 delivered to cancer cells by Prussian blue nanoparticles Synthesis and characterisation of thallium-texaphyrin nanoparticles and their assessment as potential delivery systems for Auger electron-emitting 201Tl to cancer cells. Radiotracers for in situ infection imaging: Experimental considerations for in vitro microbial uptake of gallium-68-labeled siderophores [68Ga]Ga-Schizokinen, a Potential Radiotracer for Selective Bacterial Infection Imaging Mechanisms of inclusion of thallium-201 into Prussian blue nanoparticles for nuclear medicine applications Optimised production of technetium-94m for PET imaging by proton-irradiation of phosphomolybdic acid in cyclotron liquid target Receptor-targeted peptide conjugates based on diphosphines enable preparation of 99mTc and 188Re theranostic agents for prostate cancer In Vivo PET Imaging of 89Zr-Labeled Natural Killer Cells and the Modulating Effects of a Therapeutic Antibody In Vivo Trafficking of the Anticancer Drug Tris(8-Quinolinolato) Gallium (III) (KP46) by Gallium-68/67 PET/SPECT Imaging Radionuclides for Health UK:Improving UK Access to Radionuclides for Molecular Radiotherapy Combined Vorinostat and Chloroquine Inhibit Sodium Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo Is there a role for [18F]-FMISO PET to guide dose adaptive radiotherapy in head and neck cancer? A review of the literature In vivo real-time positron emission particle tracking (PEPT) and single particle PET Radiometal-Labeled Photoactivatable Pt(IV) Anticancer Complex for Theranostic Phototherapy Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice 68Ga-Bisphosphonates for the Imaging of Extraosseous Calcification by Positron Emission Tomography Auger Electron-Emitting Radionuclides in Radiopharmaceutical Therapy Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4 Versatile Diphosphine Chelators for Radiolabeling Peptides with 99mTc and 64Cu Probing Unexpected Reactivity in Radiometal Chemistry: Indium-111-Mediated Hydrolysis of Hybrid Cyclen-Hydroxypyridinone Ligands Imaging zinc trafficking <i>in vivo</i> by positron emission tomography with zinc-62 An indium-111-labelled membrane-targeted peptide for cell tracking with radionuclide imaging Targeting integrin αvβ6 with gallium-68 tris (hydroxypyridinone) based PET probes PSMA-targeted NIR probes for image-guided detection of prostate cancer Toward Bifunctional Chelators for Thallium-201 for Use in Nuclear Medicine Correlation of hypoxia PET tracer uptake with hypoxic radioresistance in cancer cells: PET biomarkers of resistance to stereotactic radiation therapy? Non-invasive radionuclide imaging of trace metal trafficking in health and disease: “PET metallomics” A General Design Strategy Enabling the Synthesis of Hydrolysis-Resistant, Water-Stable Titanium(IV) Complexes Teaching the chemical elements in biochemistry: Elemental biology and metallomics Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99mTc radiolabelling of peptides Oxorhenium(V) and Oxotechnetium(V) Complexes of N3S Tetradentate Ligands with a Styrylpyridyl Functional Group: Toward Imaging Agents to Assist in the Diagnosis of Alzheimer's Disease In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart In vivo trafficking of a tumour-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart An Overview of Nuclear Medicine Research in the UK and the Landscape for Clinical Adoption Validation of the plasmid study to relate DNA damaging effects of radionuclides to those from external beam radiotherapy In vitro proof of concept studies of radiotoxicity from Auger electron-emitter thallium-201 Gallium: New developments and applications in radiopharmaceutics Dipeptide inhibitors of the prostate specific membrane antigen (PSMA): A comparison of urea and thiourea derivatives Options for imaging cellular therapeutics in vivo: a multi-stakeholder perspective Targeted Auger electron-emitter therapy: radiochemical approaches for thallium-201 radiopharmaceuticals Production of copper-64 using a hospital cyclotron: targetry, purification and quality analysis. The chemical tool-kit for molecular imaging with radionuclides in the age of targeted and immune therapy Optimal His-Tag Design for Efficient [99mTc(CO)3]+and [188Re(CO)3]+Labeling of Proteins for Molecular Imaging and Radionuclide Therapy by Analysis of Peptide Arrays The Radiopharmaceutical Chemistry of the Radionuclides of Gallium and Indium Evaluation of [18F]-tetrafluoroborate as a potential PET imaging agent for the human sodium/iodide symporter in a new colon carcinoma cell line, HCT116, expressing hNIS An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals View all publications
5 July 2023 Meet CARL: New Radiochemistry Laboratory opening in St Thomas' MedTech Hub The School of Biomedical Engineering & Imaging Sciences has opened a new research centre, the…