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Paola  Di Meglio

Dr Paola Di Meglio

Lecturer in Cutaneous Immunology

Research interests

  • Immunology

Biography

Dr Di Meglio received her PhD in Pharmacology from the University of Naples Federico II.

She was Visiting Postgraduate Fellow in the Section of Immunobiology at Yale University, Research Associate at St. John’s Institute of Dermatology, and Senior Investigator Scientist at the Francis Crick Institute, formerly MRC National Institute for Medical Research (NIMR) in Mill Hill. In March 2017 she became  Lecturer in Cutaneous Immunology at St John’s Institute of Dermatology. Dr Di Meglio’s research interest is in the etiopathogenesis of complex inflammatory skin conditions, with a particular focus on the mechanistic interplay between genetic, environmental and immune factors. She has also an interest in pharmacogenomics and biomarkers discovery. She identified and functionally characterized the IL23R R381Q gene variant conferring protection to psoriasis and other inflammatory diseases. Her more recent work has uncovered the beneficial role of the transcription factor and environmental sensor AhR in skin inflammation. Dr Di Meglio has been the recipient of the European Society for Dermatological Research (EASDR)/Celgene Award, and of the British Society for Investigative Dermatology (BSID) Young Investigator Award, both in 2014.  She is Section Editor in Dermatology and Skin Immunology for Pharmacological Research.

Dr Di Meglio has given over 30 invited lectures, including at the World Congress of Dermatology in 2015 and at the Montagna Symposium on the Biology of Skin in 2017.

 

    Research

    dimeglio-banner
    The Cutaneous Immunology Group

    The Cutaneous Immunology Group are based in St John's Institute of Dermatology

    News

    Outcomes of psoriasis treatment can be predicted by white blood cell response to test, scientists discover

    The way type 2 conventional dendritic cells (cDC2) respond to an in vitro test before the patient commences therapy can predict whether the therapy is going...

    Severe Psoriasis

    Enzyme found to treat inflammatory skin conditions

    Researchers have found an enzyme that plays a role in inflammatory skin diseases and could be a good target for new treatments for conditions like psoriasis.

    Psoriasis

    Study identifies cells involved in the development of eczema and psoriasis

    Researchers from St John’s Institute of Dermatology analysed cells in the blood from people with two skin diseases; psoriasis and atopic dermatitis (AD), also...

    skin

    Module lead: Pharmacogenomics and Stratified Healthcare  7BBG2012 ( MSc Genomics Medicine)

    Course teacher:
    Immune Disorders and Infection 7MCEMM03                    

    Immunology of Human Disease  6BBBI308

    Immunology and Immunotherapy of Cancer  6BBI0305

    Foundations of Biomedical Science 1 4MBBS101

      Research

      dimeglio-banner
      The Cutaneous Immunology Group

      The Cutaneous Immunology Group are based in St John's Institute of Dermatology

      News

      Outcomes of psoriasis treatment can be predicted by white blood cell response to test, scientists discover

      The way type 2 conventional dendritic cells (cDC2) respond to an in vitro test before the patient commences therapy can predict whether the therapy is going...

      Severe Psoriasis

      Enzyme found to treat inflammatory skin conditions

      Researchers have found an enzyme that plays a role in inflammatory skin diseases and could be a good target for new treatments for conditions like psoriasis.

      Psoriasis

      Study identifies cells involved in the development of eczema and psoriasis

      Researchers from St John’s Institute of Dermatology analysed cells in the blood from people with two skin diseases; psoriasis and atopic dermatitis (AD), also...

      skin

      Module lead: Pharmacogenomics and Stratified Healthcare  7BBG2012 ( MSc Genomics Medicine)

      Course teacher:
      Immune Disorders and Infection 7MCEMM03                    

      Immunology of Human Disease  6BBBI308

      Immunology and Immunotherapy of Cancer  6BBI0305

      Foundations of Biomedical Science 1 4MBBS101