Professor Marta Di Forti MD, MRCPsych, PhD Academics Supervisors Professor of Drug use, Genetics and Psychosis MRC Senior Research Fellow. Research subject areas Psychiatry Contact details marta.diforti@kcl.ac.uk
Cognitive presentation at psychosis onset through premorbid deterioration and exposure to environmental risk factors Interplay Between Childhood Maltreatment, Subclinical Post‐Traumatic Stress Symptoms, and IQ: Findings From the EU‐GEI Multicentre Case–Control Study Methylomic signature of current cannabis use in two first-episode psychosis cohorts Salivary cortisol measures across the clinical stages of psychosis: An individual participant data (IPD) meta-analysis The effect of prenatal psychotropic drug exposures on obstetric complications: 19-year population-based study A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders Bidirectional two-sample Mendelian randomization study of differential white blood cell counts and schizophrenia Corrigendum to “Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study” (Schizophrenia Research (2023) 255 (173–181), (S0920996423001147), (10.1016/j.schres.2023.03.020)) Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents The impact of schizophrenia genetic load and heavy cannabis use on the risk of psychotic disorder in the EU-GEI case-control and UK Biobank studies Association between stressful life events and psychosis relapse: a 2-year prospective study in first-episode psychosis Cannabis use and psychotic disorders in diverse settings in the Global South: findings from INTREPID II Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case–control study Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study Development and Validation of Predictive Model for a Diagnosis of First Episode Psychosis Using the Multinational EU-GEI Case-control Study and Modern Statistical Learning Methods Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis—findings from the EU-GEI study First-Episode Psychosis Patients Who Deteriorated in the Premorbid Period Do Not Have Higher Polygenic Risk Scores Than Others: A Cluster Analysis of EU-GEI Data Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis Stressful life events and relapse of psychosis: analysis of causal association in a 2-year prospective observational cohort of individuals with first-episode psychosis in the UK Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: The EU-GEI study The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case-control study Can epigenetics shine a light on the biological pathways underlying major mental disorders? Childhood maltreatment, educational attainment and IQ: findings from a multicentric case-control study of first-episode psychosis (EU-GEI) Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium Facial Emotion Recognition in Psychosis and Associations With Polygenic Risk for Schizophrenia: Findings From the Multi-Center EU-GEI Case-Control Study Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis: findings from the multinational EU-GEI study Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants with Treatment Resistance in Schizophrenia Mapping genomic loci implicates genes and synaptic biology in schizophrenia Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; The EU-GEI study Vitamin D and cardiometabolic outcomes in first episode psychosis (FEP): A prospective cohort study Adverse effects of heavy cannabis use: even plants can harm the brain Cannabis, schizophrenia genetic risk, and psychotic experiences: a cross-sectional study of 109,308 participants from the UK Biobank Cannabis use and clinical outcome in people with first-episode schizophrenia spectrum disorders over 24 months of treatment Classification of first-episode psychosis using cortical thickness: a large multicenter MRI study. COVID-19 and UK family carers: policy implications DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia Duration of Untreated Psychosis in First-Episode Psychosis is not Associated with Common Genetic Variants for Major Psychiatric Conditions: Results from the Multi-Center EU-GEI Study Early intervention in psychosis during the COVID-19 pandemic: Maudsley recommendations First-episode Psychosis and Migration in Italy: Results from a Study in the Italian Mental Health Services (Pep-Ita Study) From heavy cannabis use to psychosis: Is it time to take action? General risks of harm with cannabinoids, cannabis, and cannabis-based medicine possibly relevant to patients receiving these for pain management: an overview of systematic reviews Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study Individualized prediction of 2-year risk of relapse as indexed by psychiatric hospitalization following psychosis onset: Model development in two first episode samples International Association for the Study of Pain Presidential Task Force on Cannabis and Cannabinoid Analgesia: research agenda on the use of cannabinoids, cannabis, and cannabis-based medicines for pain management Migration history and risk of psychosis: Results from the multinational EU-GEI study Perceived major experiences of discrimination, ethnic group, and risk of psychosis in a six-country case-control study Psychosocial and pharmacological treatments for cannabis use disorder and mental health comorbidities: A narrative review View all publications
27 August 2025 Largest ever study into cannabis use investigates risk of paranoia and poor mental health in the general population New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College…