Skip to main content
Maria Eugenia Sanz

Dr Maria Eugenia Sanz

Senior Lecturer in Physical Chemistry

  • Senior Tutor

Research interests

  • Chemistry

Biography

Biological processes such as molecular recognition, membrane transport, and the folding and unfolding of proteins, occur when the molecules involved have appropriate structures and interact in a specific way. We are interested in understanding the structural preferences of biologically relevant molecules and how these preferences are affected by interactions with other molecules. Specific interests are:

Characterisation of the microsolvation of biomolecules. The aim is to determine how the first steps of solvation proceed by examining small biomolecules surrounded by an increasing number of water molecules.

Structural determination of biomolecular complexes, to examine the effect of specific binding partners on the preferred form of a biological molecule and to determine interaction sites.

Biologically relevant molecules present themselves in a variety of conformers, tautomers, and isomers that make their study particularly challenging. Our research involves the application of cutting edge spectroscopic methods (broadband rotational spectroscopy) to distinguish between different conformations and determine non-covalent intra- and intermolecular interactions. Studies are conducted in the gas phase, which provides a controlled environment where molecules can be studied in virtual isolation or interacting with other molecules one at a time. Intrinsic molecular properties are therefore revealed, and the influence of the medium can be ascertained.

Dr Sanz's Research Portal 

    Research

    chemistry molecules - blue
    Sanz Group

    The Sanz group looks at how biomolecular conformation plays a fundamental role in biological processes such as molecular recognition.

    cnes herox
    Centre for Non-Equilibrium Science (CNES)

    CNES acts as an international hub for cross-disciplinary research in non-equilibrium science.

      Research

      chemistry molecules - blue
      Sanz Group

      The Sanz group looks at how biomolecular conformation plays a fundamental role in biological processes such as molecular recognition.

      cnes herox
      Centre for Non-Equilibrium Science (CNES)

      CNES acts as an international hub for cross-disciplinary research in non-equilibrium science.