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Biography

Dr Joseph Wanford is a 'Professor Anthony Mellows Research Fellow' studying interactions between the human pathogen Klebsiella pneumoniae and the host. Dr Wanford is particularly interested in how Klebsiella switch ON and OFF their virulence determinants to resist killing by host phagocytes. A current interest is the mechanisms by which Klebsiella genetically regulate expression of the polysaccharide capsule, a major virulence factor and candidate vaccine antigen.