Prof MacCabe applies the techniques of epidemiology and population research to study the causes, consequences and treatments of psychoses, particularly in treatment resistant schizophrenia. He has led numerous multi-centre research consortia including CRESTAR, STRATA and CLEAR and has published approximately 250 research papers. He leads the Treatment Resistant Schizophrenia theme in the department.

Prof MacCabe is Academic Director of the Psychosis Clinical Academic Group, comprising all researchers and clinicians at King's Health Partners working in the field of psychosis, the largest such group in the World.

Prof MacCabe is also Honorary Consultant Psychiatrist in the South London and Maudsley NHS Foundation Trust, where he provides assessments of around 150-200 patients a year, referred from all over the UK, and he is Responsible Clinician for patients with severe and complex psychosis at the National Psychosis Unit, at the Bethlem Royal Hospital, the only national tertiary referral centre for treatment-resistant psychosis in the UK. He is clinical supervisor to one core trainee and one specialist trainee psychiatrist.

Prof MacCabe is heavily involved in teaching. He chairs the MSc in Mental Health Studies, teaches on MSc courses and at King's Medical School, and supervises postgraduate PhD students.

Prof MacCabe qualified in Medicine at Charing Cross and Westminster Medical School (MBBS, 1995) (having obtained an Intercalated BSc in Psychology and Basic Medical Sciences at UCL in 1992), and completed specialist training in Psychiatry on the Maudsley rotation from 1997 to 2004. He obtained an MRC/DoH Special Training Fellowship in Health of the Population Research in 2004, an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine in 2006 a PhD from KCL in 2008.

Prizes and Awards

2020 Psychiatric Researcher of the Year, Royal College of Psychiatrists

2019 Best Original Research Paper, British Journal of Psychiatry

2017 Mitchell B. Balter award for outstanding investigation in pharmacoepidemiology

2014 Fellowship of the Royal College of Psychiatrists

2010 Research Prize in Psychiatric Epidemiology, European Psychiatric Association

2007 BMA Medical Book Competition - Commendation in the Mental Health category for Beyond Nature and Nurture in Psychiatry

2006 Research Prize and Bronze Medal, Royal Coll. Psychiatrists

2002 Morris Markowe Public Education Prize, Royal Coll. of Psychiatrists

Research Interests

• Psychosis
• Epidemiology
• Treatment resistance
• Clinical trials
• Antipsychotics
• Clozapine

Expertise & Public Engagement

Prof MacCabe is Director of Maudsley Debates, a series of public debates on topics of public interest in the field of Mental Health.

He is a Trustee of the mental health charity, SANE.