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Gavin Bewick

Dr Gavin Bewick

Reader in Endocrinology and Metabolism

  • Acting Head, Department of Diabetes

Research interests

  • Diabetes

Biography

Dr Gavin Bewick's research interests are focused in the field of Obesity and Diabetes. He has a well-established reputation, built over the last 20 years, in studying the regulation of metabolism with a particular interest in gut hormones. His research has made important contributions to our understanding of the neuroendocrine and enteroendocrine control of appetite and body weight regulation. A key current interest of the Bewick lab is the role of the gut epithelium in the control of metabolism and the pathophysiology of diabetes and obesity. The lab is exploring the roles of diet, the microbiome and immune signaling in shaping the gut epithelium in health and disease. To do this the Bewick lab uses both pre-clinical and translational approaches encompassing methods ranging from organoid culture to single-cell transcriptomics to physiological studies.

    Research

    gut and metabolic health 1903x558
    Gut & Metabolic Health

    Our group explores the role of the gut in health and disease.

    islethero
    Islet Biology Research Group

    Our group studies the fundamental science of islets of Langerhans, from the molecular biology of beta-cells to their effects on whole body physiology. We research the mechanisms of islet dysfunction during type 2 diabetes and gestational diabetes, identify novel therapeutic targets, and work to improve islet transplantation therapy for type 1 diabetes.

      Research

      gut and metabolic health 1903x558
      Gut & Metabolic Health

      Our group explores the role of the gut in health and disease.

      islethero
      Islet Biology Research Group

      Our group studies the fundamental science of islets of Langerhans, from the molecular biology of beta-cells to their effects on whole body physiology. We research the mechanisms of islet dysfunction during type 2 diabetes and gestational diabetes, identify novel therapeutic targets, and work to improve islet transplantation therapy for type 1 diabetes.