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Cristina Garrone

Cristina Garrone

PhD Student

Research interests

  • Medicine

Biography

I obtained my undergraduate degree in Biochemistry from King’s College London, graduating in 2020. Throughout my undergraduate degree, I developed an interest in stem cell biology after completing my final year dissertation on the epigenetic regulation of muscle stem cells. Upon joining the Wellcome Trust ‘Advanced Therapies for Regenerative Medicine’ PhD Programme, I rotated across three different labs and ultimately joined the Sancho Lab to continue the rest of the PhD. My project focuses on modelling Congenital Hyperinsulinism (CHI) using patient derived induced Pluripotent Stem Cells. By recapitulating this rare monogenic disorder in vitro, I aim to elucidate the molecular mechanisms leading to aberrant β-cell function.

Research

sancholabhero
Sancho Lab

Our main goal in the Sancho lab is to decipher the fundamental regulatory networks involved in pancreatic cell fate decisions using adult and iPSCs derived organoids, and to apply this knowledge to new strategies in regenerative medicine for diabetes.

Computational Biology
Bioinformatics and Population Genomics

A computational biology lab that works on identifying the genetic and molecular mechanisms underlying variation in the human mitochondrial transcriptome

Research

sancholabhero
Sancho Lab

Our main goal in the Sancho lab is to decipher the fundamental regulatory networks involved in pancreatic cell fate decisions using adult and iPSCs derived organoids, and to apply this knowledge to new strategies in regenerative medicine for diabetes.

Computational Biology
Bioinformatics and Population Genomics

A computational biology lab that works on identifying the genetic and molecular mechanisms underlying variation in the human mitochondrial transcriptome