School of Life Course & Population Sciences

Reproductive Physiology and Medicine

Approximately 1 in 7 couples around the globe experience infertility, a growing issue as more people choose to postpone starting a family. Our research utilises sustainable pre-clinical genetically modified and longitudinal models in conjunction with human clinical samples to delve into the mechanisms that govern the hypothalamus-pituitary-ovarian axis, which acts as the primary regulator of reproduction and early embryo growth. Our goals are to investigate the effects of ageing, stress, and the environment on this reproductive axis, unveil the underlying processes of ovarian function and aging, and strive towards personalized medicine strategies to enhance the success rates of assisted reproduction.