A highly versatile high-field NMR instrument

The 700 MHz NMR spectrometer is composed of a 16.4T superconducting magnet, a quadruple resonance (¹H/¹³C/¹⁵N/³¹P) cryoprobe with z-gradients and a Bruker Avance III console. The SampleJet accessory can handle large numbers of samples in up to 49 individual tubes and five 96-well plates containing tubes of any diameter (≤ 5 mm) - the spectrometer can therefore be used for automated medium-throughput approaches such as fragment-based screening and metabolomics. This instrument can be used for a wide variety of modern, multi-dimensional structural biology experiments, and permits multi-dimensional experiments involving ³¹P, in addition to ¹³C and ¹⁵N, opening up new possibilities for the study of nucleic acids.