Dr Matthew Ryan is a Clinical Senior Lecturer in the Cardiovascular Sciences Section, School of Cardiovascular and Metabolic Medicine & Sciences. His clinical and research expertise includes clinical trials, complex and high-risk coronary intervention, mechanical circulatory support, interventions in heart failure including cardiogenic shock, coronary microvascular dysfunction, cardiovascular physiology and advanced cardiac imaging.

Dr Ryan received his medical degree from the University of Leeds in 2010, having completed an intercalated BSc in Exercise Physiology in 2008. Following initial training in North London, he commenced an NIHR Academic Clinical Fellowship at King's in 2014, whilst training across the South London Deanery. In 2018 he was awarded a British Heart Foundation Clinical Research Training Fellowship to investigate novel measures of myocardial viability during cardiac catheterisation. Following completion of his fellowship, he continued as a Clinical Lecturer, with an interest in ischaemic left ventricular dysfunction and mechanical circulatory support, with funding from the National Institute for Health Research in the UK via the CHIP-BCIS3 trial and National Institute for Health in the USA, via a collaboration with Tuft's University.

In 2024 he was awarded an Advanced Fellowship by the NIHR and MRC in Clinical Trials, including £2.4 million in funding to deliver REPRIEVED, the first randomised trial of treating coronary artery disease in patients with heart failure with preserved ejection fraction. He has also received research funding from the British Heart Foundation, National Institute for Health (USA) and Guy’s and St Thomas’ Charity.