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Marzia Malcangio

Professor Marzia Malcangio PhD

Professor of Neuropharmacology

Research interests

  • Pharmacology

Biography

My research is devoted to the study of the positive and negative modulation of pain transmission, with an emphasis on chronic pain. My research group is currently focusing on neuro-immune interactions in settings of chronic pain, covering a range of specific pain subtypes from neuropathic pain to cancer-induced bone pain. To date, I have published over 100 papers on pain and edited a book on synaptic plasticity in pain. In doing so, I have explained fundamental mechanisms and identified new targets in chronic pain, including protease and chemokines pathways in microglia and macrophage-mediated mechanisms. 

Please see my Research Staff Profile for more detail.

Find out more about my research:

TOBeATPAIN

Key Publications:

View all publications

 

Key Collaborators:

  • Professor Mauro Perretti, Queen Mary University
  • Dr Emanuele Sher, Eli Lilly
  • Professor Ray Chaudhuri, King’s College London
  • Professor Clive Ballard, Exeter University

Research

Neuron axon interactions
TOBeATPAIN

Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Neuron axon interactions
TOBeATPAIN Project 1: Neuroinflammation and pain in Alzheimer’s disease

The perception of pain is altered in AD patients and poor management of pain in conditions such as chronic inflammation may trigger distress and aggressiveness.

Project status: Ongoing

News

Pain not perceived in the same way in people with Alzheimer's Disease

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found that in a mouse model mimicking...

nervous-systen

Mechanisms underlying chronic pain in Parkinson's disease identified

Scientists from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London reported distinct pathological mechanisms behind two...

elderly lady holding head in pain csi 780x450

Research

Neuron axon interactions
TOBeATPAIN

Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Neuron axon interactions
TOBeATPAIN Project 1: Neuroinflammation and pain in Alzheimer’s disease

The perception of pain is altered in AD patients and poor management of pain in conditions such as chronic inflammation may trigger distress and aggressiveness.

Project status: Ongoing

News

Pain not perceived in the same way in people with Alzheimer's Disease

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found that in a mouse model mimicking...

nervous-systen

Mechanisms underlying chronic pain in Parkinson's disease identified

Scientists from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London reported distinct pathological mechanisms behind two...

elderly lady holding head in pain csi 780x450