Professor Graham Lord
Senior Vice-President (Health & Life Sciences)
- Executive Director of King’s Health Partners (KHP)
- Chief Academic Officer, Guy’s & St Thomas’ and King’s College Hospital NHS Trusts
Biography
Graham Lord is the Senior Vice-President, Health & Life Sciences, King’s College London, Executive Director, King’s Health Partners and Chief Academic Officer & Board Director, Guy’s & St. Thomas’ and King’s College Hospital NHS Foundation Trusts.
He was previously Vice-President at the University of Manchester and Dean of the Faculty of Biology, Medicine and Health, a Consultant Transplant Nephrologist at Manchester NHS Foundation Trust and Executive Director of the Manchester Academic Health Science Centre (2019-2024).
Graham qualified in Medicine from Cambridge. Following clinical posts at Oxford, the Hammersmith Hospital and Imperial College he was appointed as Senior Lecturer and Honorary Consultant specialising in Renal and Transplantation Medicine.
As an MRC Clinician Scientist, he undertook postdoctoral research in fundamental immune cell biology including a five-year appointment as a Visiting Fellow at Harvard University. On his return to the UK, he established a Department of Experimental Immunology at KCL and was the Director of the NIHR BRC from 2012-2019.
His clinical academic interests include multi-organ transplantation and the immunogenetics of transplant survival. Graham has significant commercial expertise, having founded companies in the US that focus on immuno-oncology, infectious diseases and autoimmunity.
He also has a long-term interest in academic healthcare systems and how they can drive improvements to human health in an equitable and sustainable manner.
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner
Lo, J. W., Schroeder, J.-H., Roberts, L. B., Mohamed, R., Cozzetto, D., Beattie, G., Omer, O. S., Ross, E. M., Heuts, F., Jowett, G. M., Read, E., Madgwick, M., Neves, J. F., Korcsmaros, T., Jenner, R. G., Walker, L. S. K., Powell, N. & Lord, G. M., 4 Nov 2024, In: Nature Communications. 15, 1, p. 9520 9520.Research output: Contribution to journal › Article › peer-review
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes
Hertweck, A., Vila De Mucha, M., Barber, P. R., Dagil, R., Porter, H., Ramos, A., Lord, G. M. & Jenner, R. G., 6 May 2022, In: Nucleic Acids Research. 50, 8, p. 4557-4573 17 p.Research output: Contribution to journal › Article › peer-review
CD90 is not constitutively expressed in functional innate lymphoid cells
Lord, G., Neves, J. F. & Schroeder, J.-H., 28 Feb 2023, (Accepted/In press) In: Frontiers in immunology.Research output: Contribution to journal › Article › peer-review
Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy
Pavlidis, P., Tsakmaki, A., Pantazi, E., Li, K., Cozzetto, D., Digby-Bell, J., Yang, F., Lo, J. W., Alberts, E., Sa, A. C. C., Niazi, U., Friedman, J., Long, A. K., Ding, Y., Carey, C. D., Lamb, C., Saqi, M., Madgwick, M., Gul, L. & Treveil, A. & 5 others, Korcsmaros, T., Macdonald, T. T., Lord, G. M., Bewick, G. & Powell, N., Dec 2022, In: Nature Communications. 13, 1, p. 5820 5820.Research output: Contribution to journal › Article › peer-review
Organoids capture tissue-specific innate lymphoid cell development in mice and humans
Jowett, G., Read, E., Roberts, L., Coman, D., Vilà González, M., Zabinski, T., Niazi, U., Antunes Dos Reis, R., Trieu, T.-J., Danovi, D., Gentleman, E., Vallier, L., Curtis, M., Lord, G. & Neves, J. F., 30 Aug 2022, In: Cell Reports. 40, 9, 111281.Research output: Contribution to journal › Article › peer-review
Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease
Omer, O. S., Hertweck, A., Roberts, L. B., Lo, J. W., Clough, J. N., Jackson, I., Pantazi, E. D., Irving, P. M., MacDonald, T. T., Pavlidis, P., Jenner, R. G. & Lord, G. M., 2022, In: Cellular and molecular gastroenterology and hepatology. 14, 3, p. 625-641 17 p.Research output: Contribution to journal › Article › peer-review
Differential regulation of allergic airway inflammation by acetylcholine
Roberts, L. B., Berkachy, R., Wayne, M., Patel, D., Schnoeller, C., Lord, G., Gounaris, K., Ryffel, B., Quesniaux, V., Darby, M., Horsnell, W. G. C. & Selkirk, M. E., 3 May 2022, (Accepted/In press) In: Frontiers in immunology.Research output: Contribution to journal › Article › peer-review
Transcription factor-driven regulation of ILC1 and ILC3
Schroeder, J.-H., Howard, J. & Lord, G., 29 Apr 2022, (Accepted/In press) In: Trends in Immunology.Research output: Contribution to journal › Review article › peer-review
Heartbreakers or healers? Innate lymphoid cells in cardiovascular disease and obesity.
Roberts, L. B., Lord, G. M. & Howard, J. K., 11 May 2022, In: Frontiers in immunology. 13, 903678.Research output: Contribution to journal › Review article › peer-review
Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study
Kaura, A., Hartley, A., Panoulas, V., Glampson, B., Shah, A. S. V., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Thursz, M. R., Elliott, P., Hemmingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Trickey, A., Sterne, J. A. & Haskard, D. O. & 10 others, Melikian, N., Francis, D. P., Koenig, W., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S., Channon, K. M., Mayet, J. & Khamis, R., 22 Feb 2022, In: PLoS Medicine. 19, 2, p. e1003911 e1003911.Research output: Contribution to journal › Article › peer-review
A population of naive-like CD4+ T cells stably polarized to the TH1 lineage
Lo, J., Vila de Mucha, M., Henderson, S., Roberts, L., Constable, L., Garrido Mesa, N., Hertweck, A., Stolarczyk, E., Houlder, E. L., Jackson, I., MacDonald, A. S., Powell, N., Neves, J. F., Howard, J., Jenner, R. & Lord, G., Apr 2022, In: European Journal of Immunology. 52, 4, p. 566-581 16 p.Research output: Contribution to journal › Article › peer-review
The Th1 cell regulatory circuitry is largely conserved between human and mouse
Henderson, S., Pullabhatla, V., Hertweck, A., de Rinaldis, E., Herrero, J., Lord, G. M. & Jenner, R. G., Nov 2021, In: Life Science Alliance. 4, 11, e202101075.Research output: Contribution to journal › Article › peer-review
Sustained post-developmental T-bet expression is critical for the maintenance of type one innate lymphoid cells in vivo
Schroeder, J.-H., Roberts, L. B., Meissl, K., Lo, J., Hromadová, D., Hayes, K., Zabinski, T., Read, E., Moreira Heliodoro, C., Antunes Dos Reis, R., Howard, J., Grencis, R., Neves, J. F., Strobl, B. & Lord, G., 29 Oct 2021, In: Frontiers in Immunology.Research output: Contribution to journal › Article › peer-review
A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling
Goldberg, R., Clough, J. N., Roberts, L. B., Sanchez, J., Kordasti, S., Petrov, N., Hertweck, A., Lorenc, A., Jackson, I., Tasker, S., Appios, A., Omer, O., Parkes, M., Prescott, N., Jenner, R. G., Irving, P. M. & Lord, G. M., 18 Dec 2021, In: Journal of Crohn's & colitis. 15, 12, p. 2054-2065 12 p., jjab103.Research output: Contribution to journal › Article › peer-review
T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells
Schroeder, J. H., Meissl, K., Hromadová, D., Lo, J. W., Neves, J. F., Howard, J. K., Helmby, H., Powell, N., Strobl, B. & Lord, G. M., 2 Feb 2021, In: Frontiers in Immunology. 11, 623324.Research output: Contribution to journal › Article › peer-review
Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes
Marshall, A., Kasturiarachchi, J., Datta, P., Guo, Y., Deltcheva, E., James, C., Brown, J., May, G., Anandagoda, N., Jackson, I., Howard, J. K., Ghazaly, E., Brooks, S., Khwaja, A., Araki, M., Araki, K., Linch, D., Lord, G. M., Enver, T. & Nimmo, R., Dec 2020, In: Scientific Reports. 10, 1, 19390.Research output: Contribution to journal › Article › peer-review
Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data
Kaura, A., Sterne, J. A. C., Trickey, A., Abbott, S., Mulla, A., Glampson, B., Panoulas, V., Davies, J., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M. & Lord, G. M. & 8 others, Melikian, N., Johnson, T., Francis, D. P., Shah, A. M., Perera, D., Kharbanda, R., Patel, R. S. & Mayet, J., 29 Aug 2020, In: The Lancet. 396, 10251, p. 623-634 12 p.Research output: Contribution to journal › Article › peer-review
Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy
Christakoudi, S., Runglall, M., Mobillo, P., Rebollo-Mesa, I., Tjir-Li, T., Viklický, O., Stahl, D., Lechler, R., Lord, G. & Hernandez Fuentes, M., 1 Aug 2020, In: EBioMedicine. 58, 102899.Research output: Contribution to journal › Article › peer-review
Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)
Kaura, A., Arnold, A. D., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Melikian, N. & Lefroy, D. C. & 6 others, Francis, D. P., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S. & Mayet, J., 7 Apr 2020, In: Journal of the American Heart Association. 9, 7, p. e013684Research output: Contribution to journal › Article › peer-review
Characterizing Innate Lymphoid Cell Phenotype and Function in Human Inflammatory Bowel Disease
Omer, O. S., Powell, N. & Lord, G. M., 1 Jan 2020, Methods in Molecular Biology. Humana Press Inc, p. 199-211 13 p. (Methods in Molecular Biology; vol. 2121).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Regulatory T-cell therapy in Crohn's disease: challenges and advances
Clough, J., Omer, O. S., Tasker, S. D., Lord, G. M. & Irving, P. M., 1 May 2020, In: Gut. 69, 5, p. 942-952 11 p.Research output: Contribution to journal › Review article › peer-review
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells
Powell, N., Pantazi, E., Pavlidis, P., Tsakmaki, A., Li, K., Yang, F., Parker, A., Pin, C., Cozzetto, D., Minns, D., Stolarczyk, E., Saveljeva, S., Mohamed, R., Lavender, P., Afzali, B., Digby-Bell, J., Tjir-Li, T., Kaser, A., Friedman, J. & MacDonald, T. T. & 2 others, Bewick, G. A. & Lord, G. M., 7 Feb 2020, In: Gut. 69, 3, p. 578-590 13 p.Research output: Contribution to journal › Review article › peer-review
The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population
The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.Research output: Contribution to journal › Article › peer-review
Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8+ effector recruitment to mucosal tissues
Zaric, M., Becker, P. D., Hervouet, C., Kalcheva, P., Doszpoly, A., Blattman, N., O'Neill, L. A., Ibarzo Yus, B., Cocita, C., Kwon, S.-Y., Baker, A. H., Lord, G. M. & Klavinskis, L., 17 May 2019, In: Nature Communications. 10, 1, 14 p., 2214.Research output: Contribution to journal › Article › peer-review
Development of a multivariable geneexpression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in crosssectional and longitudinal samples
Christakoudi, S., Runglall, M., Mobillo, P. A., Tsui, T.-L., Duff, C., Domingo Vila, C., Kamra, Y. K., Delaney, F., Montero , R., Spiridou , A., Kassimatis, T., Phin Kon, S., Tucker, B., Farmer, C., Strom, T. B., Lord, G. M., Rebollo-Mesa, I., Stahl, D., Sacks, S. & Hernandez-Fuentes, M. P. & 1 others, Chowdhury, P., 1 Mar 2019, In: EBioMedicine. 41, 0, p. 571-583 13 p.Research output: Contribution to journal › Article › peer-review
microRNA-142–mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance
Anandagoda, N., Willis, J. C. D., Hertweck, A., Roberts, L. B., Jackson, I., Gokmen, M. R., Jenner, R. G., Howard, J. K. & Lord, G. M., 1 Mar 2019, In: The Journal of clinical investigation. 129, 3, p. 1257-1271 15 p.Research output: Contribution to journal › Article › peer-review
Correction of Defective T-regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor Alpha
Goldberg, R., Scotta, C., Cooper, D., Nissim-Eliraz, E., Nir, E., Tasker, S., Irving, P. M., Sanderson, J., Lavender, P., Ibrahim, F., Corcoran, J., Prevost, T., Shpigel, N. Y., Marelli-Berg, F., Lombardi, G. & Lord, G. M., 1 May 2019, In: Gastroenterology. 156, 6, p. 1775-1787 13 p.Research output: Contribution to journal › Article › peer-review
T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function
Garrido-Mesa, N., Schroeder, J.-H., Stolarczyk, E., Gallagher, A. L., Lo, J. W., Bailey, C., Campbell, L., Sexl, V., Macdonald, T. T., Howard, J. K., Grencis, R. K., Powell, N. & Lord, G. M., Jan 2019, In: Mucosal Immunology. 12, 1, p. 51-63 13 p.Research output: Contribution to journal › Article › peer-review
Immunomodulatory role of Keratin 76 in oral and gastric cancer
Sequeira, I., Neves, J. F., Carrero, D., Peng, Q., Palasz, N., Liakath-Ali, K., Lord, G. M., Morgan, P. R., Lombardi, G. & Watt, F. M., 24 Aug 2018, In: Nature Communications. 9, 1, 15 p., 3437.Research output: Contribution to journal › Article › peer-review
Role and species-specific expression of colon T cell homing receptor GPR15 in colitis
Nguyen, L. P., Pan, J., Dinh, T. T., Hadeiba, H., O'Hara, E., Ebtikar, A., Hertweck, A., Gökmen, M. R., Lord, G. M., Jenner, R. G., Butcher, E. C. & Habtezion, A., Feb 2015, In: Nature Immunology. 16, 2, p. 207-213 7 p.Research output: Contribution to journal › Article › peer-review
Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study
United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3, Jun 2018, In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response
Marks, E., Ortiz, C., Pantazi, E., Bailey, C. S., Lord, G. M., Waldschmidt, T. J., Noelle, R. J. & Elgueta, R., 23 Dec 2016, In: Frontiers in Immunology. 7, 643Research output: Contribution to journal › Article › peer-review
Long and short term outcomes in renal cadaveric allografts: a large recipient and donor genome-wide association study. MP Hernandez-Fuentes et al.
Lord, G. M., 2018, In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation
Christakoudi, S., Runglall, M., Mobillo, P., Rebollo-Mesa, I., Tsui, T.-L., Nova-Lamperti, E., Norris, S., Kamra, Y., Hilton, R., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B., Marks, S. D. & Macphee, I. & 12 others, McKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M., Stahl, D. & Hernandez-Fuentes, M. P., 15 Sept 2018, In: Molecular and Cellular Endocrinology. 473, p. 205-216 12 p.Research output: Contribution to journal › Article › peer-review
Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management
Bierzynska, A., McCarthy, H. J., Soderquest, K., Sen, E. S., Colby, E., Ding, W. Y., Nabhan, M. M., Kerecuk, L., Hegde, S., Hughes, D., Marks, S., Feather, S., Jones, C., Webb, N. J. A., Ognjanovic, M., Christian, M., Gilbert, R. D., Sinha, M. D., Lord, G. M. & Simpson, M. & 3 others, Koziell, A. B., Welsh, G. I. & Saleem, M. A., 20 Jan 2017, In: Kidney International.Research output: Contribution to journal › Article › peer-review
MAGI2 Mutations Cause Congenital Nephrotic Syndrome
Bierzynska, A., Soderquest, K., Dean, P., Colby, E., Rollason, R., Jones, C., Inward, C. D., McCarthy, H. J., Simpson, M. A., Lord, G. M., Williams, M., Welsh, G. I., Koziell, A. B., Saleem, M. A. & NephroS, the UK study of Nephrotic Syndrome, 31 May 2017, In: Journal of the American Society of Nephrology : JASN. 28, 5, p. 1614-1621Research output: Contribution to journal › Article › peer-review
Boosting translational research in the U.K.
Anandagoda, N. & Lord, G. M., 21 Sept 2016, In: Science Translational Medicine. 8, 357, 357fs15.Research output: Contribution to journal › Article › peer-review
Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model
Alhabbab, R., Blair, P., Elgueta, R., Stolarczyk, E., Marks, E., Becker, P. D., Ratnasothy, K., Smyth, L., Safinia, N., Sharif-Paghaleh, E., O'Connell, S., Noelle, R. J., Lord, G. M., Howard, J. K., Spencer, J., Lechler, R. I. & Lombardi, G., 25 Jun 2015, In: Scientific Reports. 5, 11554.Research output: Contribution to journal › Article › peer-review
A global call for action to include gender in research impact assessment
Ovseiko, P. V., Greenhalgh, T., Adam, P., Grant, J., Hinrichs-krapels, S., Graham, K. E., Valentine, P. A., Sued, O., Boukhris, O. F., Al Olaqi, N. M., Al Rahbi, I. S., Dowd, A.-M., Bice, S., Heiden, T. L., Fischer, M. D., Dopson, S., Norton, R., Pollitt, A., Wooding, S. & Balling, G. V. & 25 others, Jakobsen, U., Kuhlmann, E., Klinge, I., Pololi, L. H., Jagsi, R., Smith, H. L., Etzkowitz, H., Nielsen, M. W., Carrion, C., Solans‐domènech, M., Vizcaino, E., Naing, L., Cheok, Q. H. N., Eckelmann, B., Simuyemba, M. C., Msiska, T., Declich, G., Edmunds, L. D., Kiparoglou, V., Buchan, A. M. J., Williamson, C., Lord, G. M., Channon, K. M., Surender, R. & Buchan, A. M., 2016, In: Health research policy and systems / BioMed Central. 14, 50.Research output: Contribution to journal › Article › peer-review
Biomarkers of tolerance in kidney transplantation – are we predicting tolerance or response to immunosuppressive treatment?
Rebollo-Mesa, I., Nova-Lamperti, E., Mobillo, P., Runglall, M., Christakoudi, S., Norris, S., Smallcombe, N., Kamra, Y., Hilton, R., Consortium, I. O. T. E., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B. & Marks, S. & 12 others, Macphee, I., McKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M. & Hernandez-Fuentes, M. P., 21 Jun 2016, (E-pub ahead of print) In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
Increased CD40 ligation and reduced BCR signalling leads to higher IL-10 production in B-cells from tolerant kidney transplant patients
www.GAMBITstudy.co.uk, Lord, G. M., Lechler, R. I. & Lombardi, G., 28 Jul 2016, In: Transplantation. TPA-2016-0165R1 .Research output: Contribution to journal › Article › peer-review
The challenges of stratifying patients for trials in inflammatory bowel disease
Biancheri, P., Powell, N., Monteleone, G., Lord, G. & MacDonald, T. T., Nov 2013, In: TRENDS IN IMMUNOLOGY. 34, 11, p. 564-571 8 p.Research output: Contribution to journal › Article › peer-review
T-bet: A bridge between innate and adaptive immunity
Lazarevic, V., Glimcher, L. H. & Lord, G. M., Nov 2013, In: NATURE REVIEWS IMMUNOLOGY. 13, 11, p. 777-789 13 p.Research output: Contribution to journal › Article › peer-review
Preventing aristolochic acid nephropathy
Anandagoda, N. & Lord, G. M., Feb 2015, In: Clinical Journal Of The American Society Of Nephrology. 10, 2, p. 167-168 2 p.Research output: Contribution to journal › Article › peer-review
Immune biomarkers: The promises and pitfalls of personalized medicine
Willis, J. C. D. & Lord, G. M., 24 Apr 2015, In: NATURE REVIEWS IMMUNOLOGY. 15, 5, p. 323-329 7 p.Research output: Contribution to journal › Article › peer-review
T-bet as a key regulator of mucosal immunity
Mohamed, R. & Lord, G. M., 1 Apr 2016, In: Immunology. 147, 4, p. 367-376 10 p.Research output: Contribution to journal › Article › peer-review
IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses
Nova Lamperti, E. A., Fanelli, G., Becker, P. D., Chana, P., Elgueta Rebolledo, R. A., Dodd, P., Lord, G. M., Lombardi, G. & Hernandez Fuentes, M. P., 22 Jan 2016, In: Scientific Reports. 6, p. 20044 20044.Research output: Contribution to journal › Article › peer-review
Role of retinoic acid in the stability of the T-helper-type 1 lineage and implications for autoimmunity
Brown, C., Esterhazy, D., Sarde, A., Pullabhatla, V., London, M., Arno, M., de Rinaldis, E., Mucida, D., Lord, G. & Noelle, R., 26 Feb 2015, In: The Lancet. 385 , Suppl 1, p. S25Research output: Contribution to journal › Poster abstract › peer-review
Interleukin 6 increases production of cytokines by colonic innate lymphoid cells in mice and patients with chronic intestinal inflammation
Powell, N., Lo, J. W., Biancheri, P., Vossenkämper, A., Pantazi, E., Walker, A. W., Stolarczyk, E., Ammoscato, F., Goldberg, R., Scott, P., Canavan, J. B., Perucha, E., Garrido-Mesa, N., Irving, P. M., Sanderson, J. D., Hayee, B., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., 1 Aug 2015, In: Gastroenterology. 149, 2, p. 456-467.e15Research output: Contribution to journal › Article › peer-review
How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?
Shankar-Hari, M. & Lord, G. M., 1 Apr 2014, In: EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 14, 3, p. 249-251 3 p.Research output: Contribution to journal › Editorial › peer-review
News
Secretaries of State for Health and Science unveil new cutting-edge scanner at King's
The Secretary of State for Health and Social Care Wes Streeting MP and the Secretary of State for Science, Innovation and Technology Peter Kyle MP met with...
Talking Leadership: Professor Graham Lord, Senior Vice-President (Health & Life Sciences)
We catch-up with Graham Lord on his first few months at King's, his ambitions for King's Health Partners, and being Senior Sponsor for Disability Inclusion.
Events
Martin Luther King Day Lecture: Confronting Racism in Health
'Confronting Racism in Health' will feature Professor Camara Jones in conversation with Professor Graham Lord on the topic of racism in health and how it can...
Please note: this event has passed.
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner
Lo, J. W., Schroeder, J.-H., Roberts, L. B., Mohamed, R., Cozzetto, D., Beattie, G., Omer, O. S., Ross, E. M., Heuts, F., Jowett, G. M., Read, E., Madgwick, M., Neves, J. F., Korcsmaros, T., Jenner, R. G., Walker, L. S. K., Powell, N. & Lord, G. M., 4 Nov 2024, In: Nature Communications. 15, 1, p. 9520 9520.Research output: Contribution to journal › Article › peer-review
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes
Hertweck, A., Vila De Mucha, M., Barber, P. R., Dagil, R., Porter, H., Ramos, A., Lord, G. M. & Jenner, R. G., 6 May 2022, In: Nucleic Acids Research. 50, 8, p. 4557-4573 17 p.Research output: Contribution to journal › Article › peer-review
CD90 is not constitutively expressed in functional innate lymphoid cells
Lord, G., Neves, J. F. & Schroeder, J.-H., 28 Feb 2023, (Accepted/In press) In: Frontiers in immunology.Research output: Contribution to journal › Article › peer-review
Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy
Pavlidis, P., Tsakmaki, A., Pantazi, E., Li, K., Cozzetto, D., Digby-Bell, J., Yang, F., Lo, J. W., Alberts, E., Sa, A. C. C., Niazi, U., Friedman, J., Long, A. K., Ding, Y., Carey, C. D., Lamb, C., Saqi, M., Madgwick, M., Gul, L. & Treveil, A. & 5 others, Korcsmaros, T., Macdonald, T. T., Lord, G. M., Bewick, G. & Powell, N., Dec 2022, In: Nature Communications. 13, 1, p. 5820 5820.Research output: Contribution to journal › Article › peer-review
Organoids capture tissue-specific innate lymphoid cell development in mice and humans
Jowett, G., Read, E., Roberts, L., Coman, D., Vilà González, M., Zabinski, T., Niazi, U., Antunes Dos Reis, R., Trieu, T.-J., Danovi, D., Gentleman, E., Vallier, L., Curtis, M., Lord, G. & Neves, J. F., 30 Aug 2022, In: Cell Reports. 40, 9, 111281.Research output: Contribution to journal › Article › peer-review
Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease
Omer, O. S., Hertweck, A., Roberts, L. B., Lo, J. W., Clough, J. N., Jackson, I., Pantazi, E. D., Irving, P. M., MacDonald, T. T., Pavlidis, P., Jenner, R. G. & Lord, G. M., 2022, In: Cellular and molecular gastroenterology and hepatology. 14, 3, p. 625-641 17 p.Research output: Contribution to journal › Article › peer-review
Differential regulation of allergic airway inflammation by acetylcholine
Roberts, L. B., Berkachy, R., Wayne, M., Patel, D., Schnoeller, C., Lord, G., Gounaris, K., Ryffel, B., Quesniaux, V., Darby, M., Horsnell, W. G. C. & Selkirk, M. E., 3 May 2022, (Accepted/In press) In: Frontiers in immunology.Research output: Contribution to journal › Article › peer-review
Transcription factor-driven regulation of ILC1 and ILC3
Schroeder, J.-H., Howard, J. & Lord, G., 29 Apr 2022, (Accepted/In press) In: Trends in Immunology.Research output: Contribution to journal › Review article › peer-review
Heartbreakers or healers? Innate lymphoid cells in cardiovascular disease and obesity.
Roberts, L. B., Lord, G. M. & Howard, J. K., 11 May 2022, In: Frontiers in immunology. 13, 903678.Research output: Contribution to journal › Review article › peer-review
Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study
Kaura, A., Hartley, A., Panoulas, V., Glampson, B., Shah, A. S. V., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Thursz, M. R., Elliott, P., Hemmingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Trickey, A., Sterne, J. A. & Haskard, D. O. & 10 others, Melikian, N., Francis, D. P., Koenig, W., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S., Channon, K. M., Mayet, J. & Khamis, R., 22 Feb 2022, In: PLoS Medicine. 19, 2, p. e1003911 e1003911.Research output: Contribution to journal › Article › peer-review
A population of naive-like CD4+ T cells stably polarized to the TH1 lineage
Lo, J., Vila de Mucha, M., Henderson, S., Roberts, L., Constable, L., Garrido Mesa, N., Hertweck, A., Stolarczyk, E., Houlder, E. L., Jackson, I., MacDonald, A. S., Powell, N., Neves, J. F., Howard, J., Jenner, R. & Lord, G., Apr 2022, In: European Journal of Immunology. 52, 4, p. 566-581 16 p.Research output: Contribution to journal › Article › peer-review
The Th1 cell regulatory circuitry is largely conserved between human and mouse
Henderson, S., Pullabhatla, V., Hertweck, A., de Rinaldis, E., Herrero, J., Lord, G. M. & Jenner, R. G., Nov 2021, In: Life Science Alliance. 4, 11, e202101075.Research output: Contribution to journal › Article › peer-review
Sustained post-developmental T-bet expression is critical for the maintenance of type one innate lymphoid cells in vivo
Schroeder, J.-H., Roberts, L. B., Meissl, K., Lo, J., Hromadová, D., Hayes, K., Zabinski, T., Read, E., Moreira Heliodoro, C., Antunes Dos Reis, R., Howard, J., Grencis, R., Neves, J. F., Strobl, B. & Lord, G., 29 Oct 2021, In: Frontiers in Immunology.Research output: Contribution to journal › Article › peer-review
A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling
Goldberg, R., Clough, J. N., Roberts, L. B., Sanchez, J., Kordasti, S., Petrov, N., Hertweck, A., Lorenc, A., Jackson, I., Tasker, S., Appios, A., Omer, O., Parkes, M., Prescott, N., Jenner, R. G., Irving, P. M. & Lord, G. M., 18 Dec 2021, In: Journal of Crohn's & colitis. 15, 12, p. 2054-2065 12 p., jjab103.Research output: Contribution to journal › Article › peer-review
T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells
Schroeder, J. H., Meissl, K., Hromadová, D., Lo, J. W., Neves, J. F., Howard, J. K., Helmby, H., Powell, N., Strobl, B. & Lord, G. M., 2 Feb 2021, In: Frontiers in Immunology. 11, 623324.Research output: Contribution to journal › Article › peer-review
Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes
Marshall, A., Kasturiarachchi, J., Datta, P., Guo, Y., Deltcheva, E., James, C., Brown, J., May, G., Anandagoda, N., Jackson, I., Howard, J. K., Ghazaly, E., Brooks, S., Khwaja, A., Araki, M., Araki, K., Linch, D., Lord, G. M., Enver, T. & Nimmo, R., Dec 2020, In: Scientific Reports. 10, 1, 19390.Research output: Contribution to journal › Article › peer-review
Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data
Kaura, A., Sterne, J. A. C., Trickey, A., Abbott, S., Mulla, A., Glampson, B., Panoulas, V., Davies, J., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M. & Lord, G. M. & 8 others, Melikian, N., Johnson, T., Francis, D. P., Shah, A. M., Perera, D., Kharbanda, R., Patel, R. S. & Mayet, J., 29 Aug 2020, In: The Lancet. 396, 10251, p. 623-634 12 p.Research output: Contribution to journal › Article › peer-review
Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy
Christakoudi, S., Runglall, M., Mobillo, P., Rebollo-Mesa, I., Tjir-Li, T., Viklický, O., Stahl, D., Lechler, R., Lord, G. & Hernandez Fuentes, M., 1 Aug 2020, In: EBioMedicine. 58, 102899.Research output: Contribution to journal › Article › peer-review
Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)
Kaura, A., Arnold, A. D., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Melikian, N. & Lefroy, D. C. & 6 others, Francis, D. P., Shah, A. M., Kharbanda, R., Perera, D., Patel, R. S. & Mayet, J., 7 Apr 2020, In: Journal of the American Heart Association. 9, 7, p. e013684Research output: Contribution to journal › Article › peer-review
Characterizing Innate Lymphoid Cell Phenotype and Function in Human Inflammatory Bowel Disease
Omer, O. S., Powell, N. & Lord, G. M., 1 Jan 2020, Methods in Molecular Biology. Humana Press Inc, p. 199-211 13 p. (Methods in Molecular Biology; vol. 2121).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Regulatory T-cell therapy in Crohn's disease: challenges and advances
Clough, J., Omer, O. S., Tasker, S. D., Lord, G. M. & Irving, P. M., 1 May 2020, In: Gut. 69, 5, p. 942-952 11 p.Research output: Contribution to journal › Review article › peer-review
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells
Powell, N., Pantazi, E., Pavlidis, P., Tsakmaki, A., Li, K., Yang, F., Parker, A., Pin, C., Cozzetto, D., Minns, D., Stolarczyk, E., Saveljeva, S., Mohamed, R., Lavender, P., Afzali, B., Digby-Bell, J., Tjir-Li, T., Kaser, A., Friedman, J. & MacDonald, T. T. & 2 others, Bewick, G. A. & Lord, G. M., 7 Feb 2020, In: Gut. 69, 3, p. 578-590 13 p.Research output: Contribution to journal › Review article › peer-review
The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population
The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.Research output: Contribution to journal › Article › peer-review
Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8+ effector recruitment to mucosal tissues
Zaric, M., Becker, P. D., Hervouet, C., Kalcheva, P., Doszpoly, A., Blattman, N., O'Neill, L. A., Ibarzo Yus, B., Cocita, C., Kwon, S.-Y., Baker, A. H., Lord, G. M. & Klavinskis, L., 17 May 2019, In: Nature Communications. 10, 1, 14 p., 2214.Research output: Contribution to journal › Article › peer-review
Development of a multivariable geneexpression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in crosssectional and longitudinal samples
Christakoudi, S., Runglall, M., Mobillo, P. A., Tsui, T.-L., Duff, C., Domingo Vila, C., Kamra, Y. K., Delaney, F., Montero , R., Spiridou , A., Kassimatis, T., Phin Kon, S., Tucker, B., Farmer, C., Strom, T. B., Lord, G. M., Rebollo-Mesa, I., Stahl, D., Sacks, S. & Hernandez-Fuentes, M. P. & 1 others, Chowdhury, P., 1 Mar 2019, In: EBioMedicine. 41, 0, p. 571-583 13 p.Research output: Contribution to journal › Article › peer-review
microRNA-142–mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance
Anandagoda, N., Willis, J. C. D., Hertweck, A., Roberts, L. B., Jackson, I., Gokmen, M. R., Jenner, R. G., Howard, J. K. & Lord, G. M., 1 Mar 2019, In: The Journal of clinical investigation. 129, 3, p. 1257-1271 15 p.Research output: Contribution to journal › Article › peer-review
Correction of Defective T-regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor Alpha
Goldberg, R., Scotta, C., Cooper, D., Nissim-Eliraz, E., Nir, E., Tasker, S., Irving, P. M., Sanderson, J., Lavender, P., Ibrahim, F., Corcoran, J., Prevost, T., Shpigel, N. Y., Marelli-Berg, F., Lombardi, G. & Lord, G. M., 1 May 2019, In: Gastroenterology. 156, 6, p. 1775-1787 13 p.Research output: Contribution to journal › Article › peer-review
T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function
Garrido-Mesa, N., Schroeder, J.-H., Stolarczyk, E., Gallagher, A. L., Lo, J. W., Bailey, C., Campbell, L., Sexl, V., Macdonald, T. T., Howard, J. K., Grencis, R. K., Powell, N. & Lord, G. M., Jan 2019, In: Mucosal Immunology. 12, 1, p. 51-63 13 p.Research output: Contribution to journal › Article › peer-review
Immunomodulatory role of Keratin 76 in oral and gastric cancer
Sequeira, I., Neves, J. F., Carrero, D., Peng, Q., Palasz, N., Liakath-Ali, K., Lord, G. M., Morgan, P. R., Lombardi, G. & Watt, F. M., 24 Aug 2018, In: Nature Communications. 9, 1, 15 p., 3437.Research output: Contribution to journal › Article › peer-review
Role and species-specific expression of colon T cell homing receptor GPR15 in colitis
Nguyen, L. P., Pan, J., Dinh, T. T., Hadeiba, H., O'Hara, E., Ebtikar, A., Hertweck, A., Gökmen, M. R., Lord, G. M., Jenner, R. G., Butcher, E. C. & Habtezion, A., Feb 2015, In: Nature Immunology. 16, 2, p. 207-213 7 p.Research output: Contribution to journal › Article › peer-review
Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study
United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3, Jun 2018, In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response
Marks, E., Ortiz, C., Pantazi, E., Bailey, C. S., Lord, G. M., Waldschmidt, T. J., Noelle, R. J. & Elgueta, R., 23 Dec 2016, In: Frontiers in Immunology. 7, 643Research output: Contribution to journal › Article › peer-review
Long and short term outcomes in renal cadaveric allografts: a large recipient and donor genome-wide association study. MP Hernandez-Fuentes et al.
Lord, G. M., 2018, In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation
Christakoudi, S., Runglall, M., Mobillo, P., Rebollo-Mesa, I., Tsui, T.-L., Nova-Lamperti, E., Norris, S., Kamra, Y., Hilton, R., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B., Marks, S. D. & Macphee, I. & 12 others, McKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M., Stahl, D. & Hernandez-Fuentes, M. P., 15 Sept 2018, In: Molecular and Cellular Endocrinology. 473, p. 205-216 12 p.Research output: Contribution to journal › Article › peer-review
Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management
Bierzynska, A., McCarthy, H. J., Soderquest, K., Sen, E. S., Colby, E., Ding, W. Y., Nabhan, M. M., Kerecuk, L., Hegde, S., Hughes, D., Marks, S., Feather, S., Jones, C., Webb, N. J. A., Ognjanovic, M., Christian, M., Gilbert, R. D., Sinha, M. D., Lord, G. M. & Simpson, M. & 3 others, Koziell, A. B., Welsh, G. I. & Saleem, M. A., 20 Jan 2017, In: Kidney International.Research output: Contribution to journal › Article › peer-review
MAGI2 Mutations Cause Congenital Nephrotic Syndrome
Bierzynska, A., Soderquest, K., Dean, P., Colby, E., Rollason, R., Jones, C., Inward, C. D., McCarthy, H. J., Simpson, M. A., Lord, G. M., Williams, M., Welsh, G. I., Koziell, A. B., Saleem, M. A. & NephroS, the UK study of Nephrotic Syndrome, 31 May 2017, In: Journal of the American Society of Nephrology : JASN. 28, 5, p. 1614-1621Research output: Contribution to journal › Article › peer-review
Boosting translational research in the U.K.
Anandagoda, N. & Lord, G. M., 21 Sept 2016, In: Science Translational Medicine. 8, 357, 357fs15.Research output: Contribution to journal › Article › peer-review
Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model
Alhabbab, R., Blair, P., Elgueta, R., Stolarczyk, E., Marks, E., Becker, P. D., Ratnasothy, K., Smyth, L., Safinia, N., Sharif-Paghaleh, E., O'Connell, S., Noelle, R. J., Lord, G. M., Howard, J. K., Spencer, J., Lechler, R. I. & Lombardi, G., 25 Jun 2015, In: Scientific Reports. 5, 11554.Research output: Contribution to journal › Article › peer-review
A global call for action to include gender in research impact assessment
Ovseiko, P. V., Greenhalgh, T., Adam, P., Grant, J., Hinrichs-krapels, S., Graham, K. E., Valentine, P. A., Sued, O., Boukhris, O. F., Al Olaqi, N. M., Al Rahbi, I. S., Dowd, A.-M., Bice, S., Heiden, T. L., Fischer, M. D., Dopson, S., Norton, R., Pollitt, A., Wooding, S. & Balling, G. V. & 25 others, Jakobsen, U., Kuhlmann, E., Klinge, I., Pololi, L. H., Jagsi, R., Smith, H. L., Etzkowitz, H., Nielsen, M. W., Carrion, C., Solans‐domènech, M., Vizcaino, E., Naing, L., Cheok, Q. H. N., Eckelmann, B., Simuyemba, M. C., Msiska, T., Declich, G., Edmunds, L. D., Kiparoglou, V., Buchan, A. M. J., Williamson, C., Lord, G. M., Channon, K. M., Surender, R. & Buchan, A. M., 2016, In: Health research policy and systems / BioMed Central. 14, 50.Research output: Contribution to journal › Article › peer-review
Biomarkers of tolerance in kidney transplantation – are we predicting tolerance or response to immunosuppressive treatment?
Rebollo-Mesa, I., Nova-Lamperti, E., Mobillo, P., Runglall, M., Christakoudi, S., Norris, S., Smallcombe, N., Kamra, Y., Hilton, R., Consortium, I. O. T. E., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B. & Marks, S. & 12 others, Macphee, I., McKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M. & Hernandez-Fuentes, M. P., 21 Jun 2016, (E-pub ahead of print) In: American Journal of Transplantation.Research output: Contribution to journal › Article › peer-review
Increased CD40 ligation and reduced BCR signalling leads to higher IL-10 production in B-cells from tolerant kidney transplant patients
www.GAMBITstudy.co.uk, Lord, G. M., Lechler, R. I. & Lombardi, G., 28 Jul 2016, In: Transplantation. TPA-2016-0165R1 .Research output: Contribution to journal › Article › peer-review
The challenges of stratifying patients for trials in inflammatory bowel disease
Biancheri, P., Powell, N., Monteleone, G., Lord, G. & MacDonald, T. T., Nov 2013, In: TRENDS IN IMMUNOLOGY. 34, 11, p. 564-571 8 p.Research output: Contribution to journal › Article › peer-review
T-bet: A bridge between innate and adaptive immunity
Lazarevic, V., Glimcher, L. H. & Lord, G. M., Nov 2013, In: NATURE REVIEWS IMMUNOLOGY. 13, 11, p. 777-789 13 p.Research output: Contribution to journal › Article › peer-review
Preventing aristolochic acid nephropathy
Anandagoda, N. & Lord, G. M., Feb 2015, In: Clinical Journal Of The American Society Of Nephrology. 10, 2, p. 167-168 2 p.Research output: Contribution to journal › Article › peer-review
Immune biomarkers: The promises and pitfalls of personalized medicine
Willis, J. C. D. & Lord, G. M., 24 Apr 2015, In: NATURE REVIEWS IMMUNOLOGY. 15, 5, p. 323-329 7 p.Research output: Contribution to journal › Article › peer-review
T-bet as a key regulator of mucosal immunity
Mohamed, R. & Lord, G. M., 1 Apr 2016, In: Immunology. 147, 4, p. 367-376 10 p.Research output: Contribution to journal › Article › peer-review
IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses
Nova Lamperti, E. A., Fanelli, G., Becker, P. D., Chana, P., Elgueta Rebolledo, R. A., Dodd, P., Lord, G. M., Lombardi, G. & Hernandez Fuentes, M. P., 22 Jan 2016, In: Scientific Reports. 6, p. 20044 20044.Research output: Contribution to journal › Article › peer-review
Role of retinoic acid in the stability of the T-helper-type 1 lineage and implications for autoimmunity
Brown, C., Esterhazy, D., Sarde, A., Pullabhatla, V., London, M., Arno, M., de Rinaldis, E., Mucida, D., Lord, G. & Noelle, R., 26 Feb 2015, In: The Lancet. 385 , Suppl 1, p. S25Research output: Contribution to journal › Poster abstract › peer-review
Interleukin 6 increases production of cytokines by colonic innate lymphoid cells in mice and patients with chronic intestinal inflammation
Powell, N., Lo, J. W., Biancheri, P., Vossenkämper, A., Pantazi, E., Walker, A. W., Stolarczyk, E., Ammoscato, F., Goldberg, R., Scott, P., Canavan, J. B., Perucha, E., Garrido-Mesa, N., Irving, P. M., Sanderson, J. D., Hayee, B., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., 1 Aug 2015, In: Gastroenterology. 149, 2, p. 456-467.e15Research output: Contribution to journal › Article › peer-review
How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?
Shankar-Hari, M. & Lord, G. M., 1 Apr 2014, In: EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 14, 3, p. 249-251 3 p.Research output: Contribution to journal › Editorial › peer-review
News
Secretaries of State for Health and Science unveil new cutting-edge scanner at King's
The Secretary of State for Health and Social Care Wes Streeting MP and the Secretary of State for Science, Innovation and Technology Peter Kyle MP met with...
Talking Leadership: Professor Graham Lord, Senior Vice-President (Health & Life Sciences)
We catch-up with Graham Lord on his first few months at King's, his ambitions for King's Health Partners, and being Senior Sponsor for Disability Inclusion.
Events
Martin Luther King Day Lecture: Confronting Racism in Health
'Confronting Racism in Health' will feature Professor Camara Jones in conversation with Professor Graham Lord on the topic of racism in health and how it can...
Please note: this event has passed.