Biography
Antonella Adami is a Research Assistant in the Comprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences.
Antonella's main role relates to the manufacturing of a Cell-based Immunotherapy for a Phase I clinical trial performing production activities ensuring GMP compliance. Processing patient samples using several assays following drug administration to monitor patients’ immunological response to the investigational therapy. Antonella is also involved in CAR T-cells research projects in the lab, particularly in the development of an allogeneic CAR T-cell therapy.
Research
CAR Mechanics Group
The CAR Mechanics Group originated in 2004 and has sought to develop and translate novel CAR T-cell strategies for the treatment of patients with refractory solid tumours. We have developed several experimental CAR approaches in addition to ancillary technologies that enable improved CAR T-cell expansion and homing to sites of disease. The CAR Mechanics group has advanced one candidate named T4 immunotherapy to Phase 1 clinical trial evaluation with funding from the Jon Moulton Charitable Foundation, Wellcome Trust and the Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust.
Research
CAR Mechanics Group
The CAR Mechanics Group originated in 2004 and has sought to develop and translate novel CAR T-cell strategies for the treatment of patients with refractory solid tumours. We have developed several experimental CAR approaches in addition to ancillary technologies that enable improved CAR T-cell expansion and homing to sites of disease. The CAR Mechanics group has advanced one candidate named T4 immunotherapy to Phase 1 clinical trial evaluation with funding from the Jon Moulton Charitable Foundation, Wellcome Trust and the Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust.