Transcriptional control of human dendritic cells differentiation.

Speaker: Dr Urszula Cytlak-Chaudhuri, Institute of Cellular Medicine, Newcastle University, 

Host: Pierre Guermonprez, pierre.guermonprez@kcl.ac.uk

Selected publications:

Ikaros family zinc finger 1 regulates dendritic cell development and function in humans.

Cytlak U, Resteu A, Bogaert D, Kuehn HS, Altmann T, Gennery A, Jackson G, Kumanovics A, Voelkerding KV, Prader S, Dullaers M, Reichenbach J, Hill H, Haerynck F, Rosenzweig SD, Collin M, Bigley V.

Nat Commun. 2018 Mar 27;9(1):1239. 

Human dendritic cell immunodeficiencies.

Bigley V, Cytlak U, Collin M.

Semin Cell Dev Biol. 2019 Feb;86:50-61. 

Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.

Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M.

J Allergy Clin Immunol. 2018 Jun;141(6):2234-2248.

Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells.

Kirkling ME, Cytlak U, Lau CM, Lewis KL, Resteu A, Khodadadi-Jamayran A, Siebel CW, Salmon H, Merad M, Tsirigos A, Collin M, Bigley V, Reizis B.

Cell Rep. 2018 Jun 19;23(12):3658-3672.e6.