London RNA Club Minisymposium proudly presents an in-person event titled RNA Biology of the Nervous System. The event is organised by Professors Eugene Makeyev and Jernej Ule.

The event is open to all King's staff and students. Registration is essential via Microsoft form.

Refreshments will be provided following the talk.

Session 1

2:00 pm

Welcome and overview

Eugene Makeyev and Jernej Ule

King’s College London

 

2:05 pm

To be or not to be translated: Existential journeys of local mRNAs

Corinne Houart

King’s College London

 

2:30 pm

Local roles of splicing factor SFPQ and intron retention in axon development and degeneration

Richard Taylor

King’s College London

 

2:45 pm

Large-scale transcriptomics analysis reveals generalized repeat expression pathology in amyotrophic lateral sclerosis

Koustav Pal

Francis Crick Institute

 

3:00 pm

Investigation of RNA-targeting CRISPR-dCas13 system to restore granulin expression in Frontotemporal Dementia

Ane Velasco Bilbao

University College London

 

3:15 pm

Optogenetic modelling of ALS C9orf72-dipeptide repeat pathology reveals new links to RNA metabolism

Tatyana Shelkovnikova

University of Sheffield

 

3:40-3:50 pm

Break

 

 

Session 2

3:50 pm

RNA regulation in healthy and degenerating neurons

Marina Chekulaeva

Max Delbrück Center for Molecular Medicine

 

4:15 pm

Altered nucleocytoplasmic mRNA partitioning leads to the uncoupling of the proteome from the transcriptome in neural stem cell quiescence

Alice Rossi

Francis Crick Institute

 

4:30 pm

The RNA biology of chronic sleep deprivation

Charlotte Capitanchik

King’s College London

 

4:45 pm

Examining the effect of sleep and cognitive stimulation on mRNA translation in cortical pyramidal neurons

Martin Smith

University of Surrey

 

5:00 pm

Alternative splicing of the Mu Opioid Receptor plays a major role in addiction to opioids

Peter McNaughton

King’s College London

 

5:15 pm

Closing remarks

Eugene Makeyev and Jernej Ule

 

5:16 pm – until supplies last

Pizza and beer