Elemental Bioimaging is a rapidly expanding field with significant value for fundamental scientific questions regarding cell fate and health, trace element metabolism, and for translational science in diagnosis, prognosis, and therapy. Supported by new analytical advances in mass spec imaging and with the further addition of spectroscopy and microscopy, we can now see elements within complex biological matrices. This is complemented by information about associated molecules and their structures, covering ever-greater sensitivities and spatial resolutions to address structural, functional and quantitative questions from the atomic level to whole body processes.

This workshop is intended to introduce the biological community to a new set of analytical tools being offered at the London Metallomics Facility (LMF) and how such analytics can be integrated into the existing portfolio of imaging techniques provided by the Nikon Imaging Centre (NIC), Microscopy Innovation Centre (MIC) and Centre for Ultrastructural Imaging (CUI). 

This event is open to King's staff, students and external delegates. It is free to attend but please register via eventbrite.

 

Agenda:

9.00 am 

Registration and coffee

9.30 am

Welcome and introduction to LMF - Theodora Stewart, LMF

Introduction to the NIC - Dan Matthews, NIC

Introduction to the MIC - James Levitt, MIC

Introduction to the CUI - Roland Fleck, CUI

10.00 am

Phil Blower, Department of Imaging, Chemistry & Biology, KCL

Whole body metallomics in vivo at the whole body level using positron emission tomography

10.25 am

Michael Watkinson, School of Chemical and Physical Sciences, Keele University

Targeted probes for the detection of mobile zinc in cellulo

10.50 am

Coffee, tea and biscuits

11.10 am

Mary Burkitt-Gray, Chelsea Technologies Group Ltd.

Correlative analysis of biologically-synthesised quantum dots

11.35 am

Thibaut Van Acker, Department of Chemistry, Ghent University

Single-cell imaging via LA-ICP-MS using a low-dispersion interface

12.00 pm

Stijn J. M. Van Malderen, Department of Chemistry, Ghent University 

Ciprian Stremtan, EMEA Laser Ablation Specialist, Teledyne CETAC Technologies

Data interrogation tools for cross-modality elemental imaging

12.25 pm

Lunch

13.30 pm

Discussion, networking & new collaborations

 

The full abstract book is available as a PDF here