Subject areas:
Cell biology, Cancer
Funding type:
Stipend.
Living cost.
Tuition fee.
Bench Fees / Research Training & Support Grant.
Country:
Home Fee Status Students.
This project will define how adhesion receptors in lung cancer cells contribute to regulation of tumour-immune cell interactions using advanced 3D models.
Award details
Lung cancer is the leading cause of cancer death worldwide. Despite advances in treatment options, prognosis remains poor in part due to the heterogeneous nature of the disease. Our recent work has identified the coxsackievirus adenovirus receptor (CAR) as an important cell adhesion receptor controlling lung cancer progression and tumour-immune cell interactions. This project aims to define the mechanisms by which CAR mediates lung cancer progression, using state of the art 3D models and advanced microscopy, molecular and ‘omics approaches. Novel agents to perturb CAR-dependent co-operation with the immune compartment will be used to validate CAR as a potential therapeutic target. The outcome of this project will provide new mechanistic insight into lung cancer-immune cell interactions in physiologically relevant settings and pave the way for new targets for intervention.
Sponsor: This is funded by a generous donation from a GSTT patient; funds are held by the GST Charity
Duration: 3 years
Start date: 1 October 2025
Eligibility criteria
English Language Requirements:
Band D
Application process
Please submit an application for the Basic and Medical Bioscience Research MPhil/PhD (Full-time) using the KCL online application form.
Before completing the application click here for information about the programme, requirements and details of what documentation and information needs to be included in your application.
Please include in your application:
- Details of previous employment where applicable
- A 500-word personal statement outlining your motivation for undertaking postgraduate research and in the advertised project should be uploaded to the Supporting statement section.
- References: two supporting references are required with at least one academic. Professional references will be accepted if you have completed your qualifications over five years ago. The prospective supervisors must not be given as referees. Applicant must ensure that their chosen referees are made aware of the requirement to submit the reference before the application deadline.
In the application form under ‘Funding information’: Please select option 5 ‘I am applying for a funding award or scholarship administered by King’s College London’ and under ‘Award Scheme Code or Name’ add 2025/BMBS/07. Failing to include this code might result in you not being considered for this funding.
It is recommended to informally approach Professor Maddy Parsons (maddy.parsons@kcl.ac.uk) before making an application. For administrative and application process enquiries please contact BMBS PGR.