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Maria Jimenez-Sanchez

Dr Maria Jimenez-Sanchez PhD

MRC Career Development Fellow

Research interests

  • Neuroscience

Biography

My lab is interested in studying the mechanisms that prevent protein misfolding and accumulation in neurodegenerative diseases, such as molecular chaperones and autophagy. While the relevance of these mechanisms to neurodegeneration has been widely studied in neurons, their importance in glial cells such as astrocytes, has not received as much attention so far. Research in the lab is funded by an MRC Career Development Award to study chaperones as molecular targets to prevent Alzheimer’s disease in the context of astrocyte-neuron communication.

Please see my Research Staff Profile for more detail.

Find out more about my research:

Key Publications:

View all publications

Key Collaborators:

  • Dr Wendy Noble, King's College London
  • Dr Beatriz Gomez Perez-Nievas, King's College London
  • Professor Diane Hanger, King's College London

Research

Glial cells and Neurodegeneration
Maria Jimenez-Sanchez Research Group

We investigate the role of molecular chaperones and autophagy in glial cells. Chaperones and autophagy are essential cellular mechanisms to prevent the accumulation of misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease. We study how these mechanisms work in astrocytes in the context of neurodegeneration. The group is based in the Maurice Wohl Institute in the Department of Basic and Clinical Neuroscience at King's College London

Features

Celebrating Neuroscience Research this Brain Awareness Week

This year, Brain Awareness Week was held from 14 to 22 March 2022. Brain Awareness Week is the global campaign to foster public enthusiasm and support for...

neurons3

Research

Glial cells and Neurodegeneration
Maria Jimenez-Sanchez Research Group

We investigate the role of molecular chaperones and autophagy in glial cells. Chaperones and autophagy are essential cellular mechanisms to prevent the accumulation of misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease. We study how these mechanisms work in astrocytes in the context of neurodegeneration. The group is based in the Maurice Wohl Institute in the Department of Basic and Clinical Neuroscience at King's College London

Features

Celebrating Neuroscience Research this Brain Awareness Week

This year, Brain Awareness Week was held from 14 to 22 March 2022. Brain Awareness Week is the global campaign to foster public enthusiasm and support for...

neurons3